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Literature DB >> 5685878

The purification and some properties of a beta-lactamase (cephalosporinase) synthesized by Enterobactercloacae.

Abstract

1. A beta-lactamase has been purified from a strain of Enterobacter cloacae. 2. This enzyme is about eighty times as active against cephaloridine as against benzylpenicillin or ampicillin. 3. The enzyme has a net positive charge at pH8.0 and a molecular weight of about 14000. 4. An approximate amino acid composition of the enzyme is reported.

Entities: Chemical Species

Mesh：

Substances：

Year: 1968 PMID： 5685878 PMCID： PMC1186840 DOI： 10.1042/bj1090469

Source DB: PubMed Journal: Biochem J ISSN： 0264-6021 Impact factor: 3.857

14 in total

1. Observations on the nature, distribution, and significance of cephalosporinase.

Authors: P C FLEMING; M GOLDNER; D G GLASS
Journal: Lancet Date: 1963-06-29 Impact factor: 79.321

2. Differences between pencillinases from gram-positive and gram-negative bacteria.

Authors: J T SMITH; J M HAMILTON-MILLER
Journal: Nature Date: 1963-03-09 Impact factor: 49.962

3. The oxidation of ribonuclease with performic acid.

Authors: C H HIRS
Journal: J Biol Chem Date: 1956-04 Impact factor: 5.157

4. [Purification and physicochemical characteristics of the penicillinase of Bacillus cereus].

Authors: M R POLLOCK; A M TORRIANI
Journal: C R Hebd Seances Acad Sci Date: 1953-07-20

5. Micro-iodometric assay for penicillinase.

Authors: R P NOVICK
Journal: Biochem J Date: 1962-05 Impact factor: 3.857

Review 6. The biochemistry and function of beta-lactamase (penicillinase).

Authors: N Citri; M R Pollock
Journal: Adv Enzymol Relat Areas Mol Biol Date: 1966

7. Penicillinase synthesis controlled by infectious R factors in Enterobacteriaceae.

Authors: N Datta; P Kontomichalou
Journal: Nature Date: 1965-10-16 Impact factor: 49.962

8. Interaction of cephaloridine with penicillinase-producing gram-negative bacteria.

Authors: J M Hamilton-Miller; J T Smith; R Knox
Journal: Nature Date: 1965-10-16 Impact factor: 49.962

9. Inducible beta-lactamase in Enterobacter.

Authors: T D Hennessey
Journal: J Gen Microbiol Date: 1967-11

10. The purification and properties of a penicillinase whose synthesis is mediated by an R-factor in Escherichia coli.

Authors: N Datta; M H Richmond
Journal: Biochem J Date: 1966-01 Impact factor: 3.857

16 in total

1. Enzymatic and immunological characterization of a new cephalosporinase from Enterobacter aerogenes.

Authors: R Letarte; M Devaud-Felix; J C Pechere; D Allard-Leprohon
Journal: Antimicrob Agents Chemother Date: 1977-08 Impact factor: 5.191

2. Improvement of the specificity of an antiserum to -lactamase by absorption with a mutant which does not produce the enzyme.

Authors: G W Ross; M G Boulton
Journal: J Bacteriol Date: 1972-12 Impact factor: 3.490

3. Purification and properties of a cephalosporinase from Enterobacter cloacae.

Authors: S Minami; M Inoue; S Mitsuhashi
Journal: Antimicrob Agents Chemother Date: 1980-12 Impact factor: 5.191

4. Role of the 7 alpha-methoxy and side-chain carboxyl of moxalactam in beta-lactamase stability and antibacterial activity.

Authors: K Murakami; T Yoshida
Journal: Antimicrob Agents Chemother Date: 1981-01 Impact factor: 5.191

5. Resistance of Escherichia coli to penicillins. VI. Purification and characterization of the chromosomally mediated penicillinase present in ampA-containing strains.

Authors: E B Linström; H G Boman; B B Steele
Journal: J Bacteriol Date: 1970-01 Impact factor: 3.490

6. Cloning and expression of the imipenem-hydrolyzing beta-lactamase operon from Pseudomonas maltophilia in Escherichia coli.

Authors: J Dufresne; G Vézina; R C Levesque
Journal: Antimicrob Agents Chemother Date: 1988-06 Impact factor: 5.191

7. Paradoxical antibacterial activities of beta-lactams against Proteus vulgaris: mechanism of the paradoxical effect.

Authors: Y Ikeda; T Nishino
Journal: Antimicrob Agents Chemother Date: 1988-07 Impact factor: 5.191

8. Some relationships between R-factor and chromosomal -lactamase in Gram-negative bacteria.

Authors: J W Dale; J T Smith
Journal: Biochem J Date: 1971-07 Impact factor: 3.857

9. Comparative study of seven cephalosporins: susceptibility to beta-lactamases and ability to penetrate the surface layers of Escherichia coli.

Authors: M H Richmond; S Wotton
Journal: Antimicrob Agents Chemother Date: 1976-08 Impact factor: 5.191

10. Paradoxical antibacterial activity of cefmenoxime against Proteus vulgaris.

Authors: Y Ikeda; T Nishino; T Tanino
Journal: Antimicrob Agents Chemother Date: 1987-06 Impact factor: 5.191