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Literature DB >> 4942448

Some relationships between R-factor and chromosomal -lactamase in Gram-negative bacteria.

Abstract

1. The beta-lactamases specified by Klebsiella aerogenes 418 and the R-factor R-7268 have been partially purified. 2. The molecular weights of the K. aerogenes strains 418 and 373, Aerobacter cloacae 53, R-7268 and R-TEM beta-lactamases were all about 20000; that of the enzymes from Escherichia coli strains 419 and 214T was about 31000. 3. These enzymes were also compared by means of their K(m) values for benzylpenicillin and ampicillin, and their behaviour on starch-gel electrophoresis. 4. The beta-lactamases specified by the two Klebsiella strains, the Aerobacter strain, and the R-factors R-TEM and R-7268 were found to comprise a broadly similar group. However, within this group, only two enzymes seemed to be identical, namely those specified by the two R-factors. The two E. coli strains produce identical beta-lactamases which are very different from the ;Klebsiella/Aerobacter-type' enzymes.

Entities: Chemical Species

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Year: 1971 PMID： 4942448 PMCID： PMC1176990 DOI： 10.1042/bj1230507

Source DB: PubMed Journal: Biochem J ISSN： 0264-6021 Impact factor: 3.857

32 in total

1. A method for determining the sedimentation behavior of enzymes: application to protein mixtures.

Authors: R G MARTIN; B N AMES
Journal: J Biol Chem Date: 1961-05 Impact factor: 5.157

2. Starch gel electrophoresis in a discontinous system of buffers.

Authors: M D POULIK
Journal: Nature Date: 1957-12-28 Impact factor: 49.962

3. Mutants of Escherichia coli requiring methionine or vitamin B12.

Authors: B D DAVIS; E S MINGIOLI
Journal: J Bacteriol Date: 1950-07 Impact factor: 3.490

4. Comparison of penicillinases produced by R factors isolated from ampicillin-resistant gram-negative bacteria.

Authors: T Ooka; H Hashimoto; S Mitsuhashi
Journal: Jpn J Microbiol Date: 1970-03

5. The relation of resistance transfer factors to the F-factor (sex-factor) of Escherichia coli K12.

Authors: E Meynell; N Datta
Journal: Genet Res Date: 1966-02 Impact factor: 1.588

6. Interaction of cephaloridine with penicillinase-producing gram-negative bacteria.

Authors: J M Hamilton-Miller; J T Smith; R Knox
Journal: Nature Date: 1965-10-16 Impact factor: 49.962

7. A comparative study of eight distinct beta-lactamases synthesized by gram-negative bacteria.

Authors: G W Jack; M H Richmond
Journal: J Gen Microbiol Date: 1970-04

8. Resistance of Escherichia coli to Penicillins I. Genetic Study of Some Ampicillin-Resistant Mutants.

Authors: K G Eriksson-Grennberg; H G Boman; J A Jansson; S Thorén
Journal: J Bacteriol Date: 1965-07 Impact factor: 3.490

9. Characterization of the -lactamase specified by the resistance factor R-1818 in E. coli K12 and other Gram-negative bacteria.

Authors: J W Dale
Journal: Biochem J Date: 1971-07 Impact factor: 3.857

10. The purification and properties of a penicillinase whose synthesis is mediated by an R-factor in Escherichia coli.

Authors: N Datta; M H Richmond
Journal: Biochem J Date: 1966-01 Impact factor: 3.857

16 in total

1. Plasmid-determined beta-lactamase indistinguishable from the chromosomal beta-lactamase of Escherichia coli.

Authors: M M Bobrowski; M Matthew; P T Barth; N Datta; N J Grinter; A E Jacob; P Kontomichalou; J W Dale; J T Smith
Journal: J Bacteriol Date: 1976-01 Impact factor: 3.490

2. Enzymatic and immunological characterization of a new cephalosporinase from Enterobacter aerogenes.

Authors: R Letarte; M Devaud-Felix; J C Pechere; D Allard-Leprohon
Journal: Antimicrob Agents Chemother Date: 1977-08 Impact factor: 5.191

3. The comparative performance of beta-lactam antibiotics against ampicillin sensitive Escherichia coli in conditions simulating those of the infected urinary bladder.

Authors: D Greenwood; F O'Grady
Journal: Br J Exp Pathol Date: 1974-06

Some relationships between R-factor and chromosomal -lactamase in Gram-negative bacteria.

1. A method for determining the sedimentation behavior of enzymes: application to protein mixtures.

2. Starch gel electrophoresis in a discontinous system of buffers.

3. Mutants of Escherichia coli requiring methionine or vitamin B12.

4. Comparison of penicillinases produced by R factors isolated from ampicillin-resistant gram-negative bacteria.

5. The relation of resistance transfer factors to the F-factor (sex-factor) of Escherichia coli K12.

6. Interaction of cephaloridine with penicillinase-producing gram-negative bacteria.

7. A comparative study of eight distinct beta-lactamases synthesized by gram-negative bacteria.

8. Resistance of Escherichia coli to Penicillins I. Genetic Study of Some Ampicillin-Resistant Mutants.

9. Characterization of the -lactamase specified by the resistance factor R-1818 in E. coli K12 and other Gram-negative bacteria.

10. The purification and properties of a penicillinase whose synthesis is mediated by an R-factor in Escherichia coli.

1. Plasmid-determined beta-lactamase indistinguishable from the chromosomal beta-lactamase of Escherichia coli.

2. Enzymatic and immunological characterization of a new cephalosporinase from Enterobacter aerogenes.

3. The comparative performance of beta-lactam antibiotics against ampicillin sensitive Escherichia coli in conditions simulating those of the infected urinary bladder.

4. R-factor-mediated beta-lactamases that hydrolyze oxacillin: evidence for two distinct groups.

5. Characterization of R factor beta-lactamases by the acidimetric method.

6. Relation of R factor and chromosomal beta-lactamase with the periplasmic space.

Review 7. A functional classification scheme for beta-lactamases and its correlation with molecular structure.

8. Purification and properties of a new beta-lactamase from Pseudomonas cepacia.

9. Penicillinases of Klebsiella pneumoniae and their phylogenetic relationship to penicillinases mediated by R factors.

10. Molecular specificities of R factor-determined beta-lactamases: correlation with plasmid compatibility.