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Literature DB >> 5676403

Inactivation and phosphorylation of kanamycin by drug-resistant Staphylococcus aureus.

Abstract

The cell-free system of clinical isolates of drug-resistant Staphylococcus aureus inactivated kanamycin, and the inactivated product was identified with kanamycin-3'-phosphate, in which the C-3-OH of the 6-amino-6-deoxy-d-glucose moiety of kanamycin was phosphorylated.

Entities: Chemical Species

Mesh：

Substances：
Enzymes
Kanamycin

Year: 1968 PMID： 5676403 PMCID： PMC547641 DOI： 10.1128/am.16.9.1282-1284.1968

Source DB: PubMed Journal: Appl Microbiol ISSN： 0003-6919

9 in total

1. Phosphorylative inactivation of aminoglycosidic antibiotics by Escherichia coli carrying R factor.

Authors: H Umezawa; M Okanishi; S Kondo; K Hamana; R Utahara; K Maeda; S Mitsuhashi
Journal: Science Date: 1967-09-29 Impact factor: 47.728

2. Chloramphenicol-, dihydrostreptomycin-, and kanamycin-inactivating enzymes from multiple drug-resistant Escherichia coli carrying episome 'R'.

Authors: S Okamoto; Y Suzuki
Journal: Nature Date: 1965-12-25 Impact factor: 49.962

3. Isolation of kanamycin and paromamine inactivated by E. coli carrying R factor.

Authors: S Kondo; M Okanishi; R Utahara; K Maeda; H Umezawa
Journal: J Antibiot (Tokyo) Date: 1968-01 Impact factor: 2.649

4. Studies on inactivation of kanamycin and resistances of E. coli.

Authors: M Okanishi; S Kondo; Y Suzuki; S Okamoto; H Umezawa
Journal: J Antibiot (Tokyo) Date: 1967-07 Impact factor: 2.649

5. Isolation and structure of kanamycin inactivated by a cell free system of kanamycin-resistant E. coli.

Authors: H Umezawa; M Okanishi; R Utahara; K Maeda; S Kondo
Journal: J Antibiot (Tokyo) Date: 1967-07 Impact factor: 2.649

6. Biochemical studies on the activity of thiophenicol.

Authors: T Nishimura; H Yamaguchi; N Tanaka
Journal: J Antibiot (Tokyo) Date: 1966-07 Impact factor: 2.649

7. The enzymatic acetylation of chloramphenicol by extracts of R factor-resistant Escherichia coli.

Authors: W V Shaw
Journal: J Biol Chem Date: 1967-02-25 Impact factor: 5.157

8. Basis of chloramphenicol resistance in naturally isolated resistant staphylococci.

Authors: Y Suzuki; S Okamoto; M Kono
Journal: J Bacteriol Date: 1966-09 Impact factor: 3.490

9. Inactivation of kanamycin, neomycin, and streptomycin by enzymes obtained in cells of Pseudomonas aeruginoa.

Authors: O Doi; M Ogura; N Tanaka; H Umezawa
Journal: Appl Microbiol Date: 1968-09

9 in total

12 in total

Review 1. Antibiotic resistance plasmids of Staphylococcus aureus and their clinical importance.

Authors: R W Lacey
Journal: Bacteriol Rev Date: 1975-03

Review 2. Genetic basis, epidemiology, and future significance of antibiotic resistance in Staphylococcus aureus: a review.

Authors: R W Lacey
Journal: J Clin Pathol Date: 1973-12 Impact factor: 3.411

3. Functional and kinetic analysis of the phosphotransferase CapP conferring selective self-resistance to capuramycin antibiotics.

Authors: Zhaoyong Yang; Masanori Funabashi; Koichi Nonaka; Masahiko Hosobuchi; Tomoyuki Shibata; Pallab Pahari; Steven G Van Lanen
Journal: J Biol Chem Date: 2010-03-04 Impact factor: 5.157

4. Microbial transformation of antibiotics: phosphorylation of clindamycin by Streptomyces coelicolor Müller.

Authors: J H Coats; A D Argoudelis
Journal: J Bacteriol Date: 1971-10 Impact factor: 3.490

5. New plasmid-mediated nucleotidylation of aminoglycoside antibiotics in Staphlococcus aureus.

Authors: F Le Goffic; A Martel; M L Capmau; B Baca; P Goebel; H Chardon; C J Soussy; J Duval; D H Bouanchaud
Journal: Antimicrob Agents Chemother Date: 1976-08 Impact factor: 5.191

6. Isolation and characterization of a kanamycin resistance plasmid from Staphylococcus aureus.

Authors: P W Stiffler; H M Sweeney; M Schneider; S Cohen
Journal: Antimicrob Agents Chemother Date: 1974-10 Impact factor: 5.191

7. Activity of lividomycin against Pseudomonas aeruginosa: its inactivation by phosphorylation induced by resistant strains.

Authors: F Kobayashi; M Yamaguchi; S Mitsuhashi
Journal: Antimicrob Agents Chemother Date: 1972-01 Impact factor: 5.191

Inactivation and phosphorylation of kanamycin by drug-resistant Staphylococcus aureus.

1. Phosphorylative inactivation of aminoglycosidic antibiotics by Escherichia coli carrying R factor.

2. Chloramphenicol-, dihydrostreptomycin-, and kanamycin-inactivating enzymes from multiple drug-resistant Escherichia coli carrying episome 'R'.

3. Isolation of kanamycin and paromamine inactivated by E. coli carrying R factor.

4. Studies on inactivation of kanamycin and resistances of E. coli.

5. Isolation and structure of kanamycin inactivated by a cell free system of kanamycin-resistant E. coli.

6. Biochemical studies on the activity of thiophenicol.

7. The enzymatic acetylation of chloramphenicol by extracts of R factor-resistant Escherichia coli.

8. Basis of chloramphenicol resistance in naturally isolated resistant staphylococci.

9. Inactivation of kanamycin, neomycin, and streptomycin by enzymes obtained in cells of Pseudomonas aeruginoa.

Review 1. Antibiotic resistance plasmids of Staphylococcus aureus and their clinical importance.

Review 2. Genetic basis, epidemiology, and future significance of antibiotic resistance in Staphylococcus aureus: a review.

3. Functional and kinetic analysis of the phosphotransferase CapP conferring selective self-resistance to capuramycin antibiotics.

4. Microbial transformation of antibiotics: phosphorylation of clindamycin by Streptomyces coelicolor Müller.

5. New plasmid-mediated nucleotidylation of aminoglycoside antibiotics in Staphlococcus aureus.

6. Isolation and characterization of a kanamycin resistance plasmid from Staphylococcus aureus.

7. Activity of lividomycin against Pseudomonas aeruginosa: its inactivation by phosphorylation induced by resistant strains.

8. Lividomycin resistance in staphylococci by enzymatic phosphorylation.

9. Inactivation of kanamycin, neomycin, and streptomycin by enzymes obtained in cells of Pseudomonas aeruginoa.

10. Antibacterial activity of lividomycin toward R factor-resistant strains of Escherichia coli.