Literature DB >> 567477

Ligand-binding propeties of the muscarinic acetylcholine receptor in mouse neuroblastoma cells.

P G Strange, N J Birdsall, A S Burgen.   

Abstract

1. Muscarinic acetylcholine receptors in a plasma-membrane fraction derived from mouse neuroblastoma clone NIE-115 bind [3-3H]quinuclidinyl benzilate according to the Law of Mass Action (Kdissociation 40 pM, h0.96). 2. Antagonist and agonist binding to the receptor was studied by displacement of [3-3H]quinuclidinyl benzilate with non-radioactive ligands. The data show good agreement with similar data obtained on rat brain and ideal smooth muscle [Birdsall & Hulme (1976) J. Neurochem. 27, 7-16] indicating that the receptor is very similar in these three tissues.

Entities:  

Mesh：

Substances：

Year:  1978        PMID： 567477      PMCID： PMC1185723          DOI： 10.1042/bj1720495

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  18 in total

1.  Antipsychotics block muscarinic acetylcholine receptor-mediated cyclic GMP formation in cultured mouse neuroblastoma cells.

Authors:  E Richelson
Journal:  Nature       Date:  1977-03-24       Impact factor: 49.962

2.  Occupancy of muscarinic acetylcholine receptors stimulates a guanylate cyclase in neuroblastoma cells.

Authors:  P G Strange; N J Birdsall; A S Burgen
Journal:  Biochem Soc Trans       Date:  1977       Impact factor: 5.407

3.  Ligand specificity and characteristics of the beta-adrenergic receptor in turkey erythrocyte plasma membranes.

Authors:  A Levitzki; N Sevilia; D Atlas; M L Steer
Journal:  J Mol Biol       Date:  1975-09-05       Impact factor: 5.469

4.  Protein measurement with the Folin phenol reagent.

Authors:  O H LOWRY; N J ROSEBROUGH; A L FARR; R J RANDALL
Journal:  J Biol Chem       Date:  1951-11       Impact factor: 5.157

Review 5.  Neuron models.

Authors:  B Hamprecht
Journal:  Angew Chem Int Ed Engl       Date:  1976-04       Impact factor: 15.336

6.  Comparison of surface membranes isolated from cultured murine neuroblastoma cells in the differentiated or undifferentiated state.

Authors:  R Truding; M L Shelanski; M P Daniels; P Morell
Journal:  J Biol Chem       Date:  1974-06-25       Impact factor: 5.157

7.  Absolute configuration of 3-quinuclidinyl benzilate and the behavioral effect in the dog of the optical isomers.

Authors:  A Meyerhöffer
Journal:  J Med Chem       Date:  1972-09       Impact factor: 7.446

8.  Solubilisation of atropine-binding material from brain.

Authors:  S Carson; S Godwin; J Massoulie; G Kato
Journal:  Nature       Date:  1977-03-10       Impact factor: 49.962

9.  Neurotransmitter synthesis by neuroblastoma clones (neuroblast differentiation-cell culture-choline acetyltransferase-acetylcholinesterase-tyrosine hydroxylase-axons-dendrites).

Authors:  T Amano; E Richelson; M Nirenberg
Journal:  Proc Natl Acad Sci U S A       Date:  1972-01       Impact factor: 11.205

10.  Muscarinic cholinergic binding in rat brain.

Authors:  H I Yamamura; S H Snyder
Journal:  Proc Natl Acad Sci U S A       Date:  1974-05       Impact factor: 11.205
View more
  12 in total

1.  A method for measuring relative changes in guanosine 3':5'-cyclic monophosphate in mouse neuroblastoma cells on muscarinic cholinergic stimulation.

Authors:  P G Strange
Journal:  Biochem J       Date:  1978-11-15       Impact factor: 3.857

2.  Muscarinic cholinergic receptor binding in rat mast cells.

Authors:  E Masini; R Fantozzi; P Blandina; S Brunelleschi; P F Mannaioni
Journal:  Agents Actions       Date:  1983-06

3.  Effect of a phosphodiesterase inhibitor on cyclic GMP changes induced by muscarinic agonists in mouse neuroblastoma cells [proceedings].

Authors:  P G Strange; T Bennett
Journal:  Br J Pharmacol       Date:  1978-11       Impact factor: 8.739

4.  Binding studies with 3H-atropine in intact isolated guinea pig gastric mucosal cells.

Authors:  M Albinus; K F Sewing
Journal:  Agents Actions       Date:  1980-04

5.  Identification and characterization of the beta-adrenergic receptor on neuroblastoma x glioma hybrid NG108-15 cells.

Authors:  A Ghahary; K W Cheng
Journal:  Cell Mol Neurobiol       Date:  1990-09       Impact factor: 5.046

6.  Characterization of muscarinic acetylcholine receptors on intact neuroblastoma x glioma NG108-15 cell upon induced differentiation.

Authors:  A Ghahary; K W Cheng
Journal:  Mol Cell Biochem       Date:  1989-04-11       Impact factor: 3.396

7.  The interaction of amine local anaesthetics with muscarinic receptors.

Authors:  W J Taylor; A Wolf; J M Young
Journal:  Br J Pharmacol       Date:  1980       Impact factor: 8.739

8.  Estimation of the density of sodium entry sites in frog skin epithelium from the uptake of [3H]benzamil.

Authors:  J Aceves; A W Cuthbert; J M Edwardson
Journal:  J Physiol       Date:  1979-10       Impact factor: 5.182

9.  Antagonism by antidepressants of muscarinic acetylcholine receptors of human brain.

Authors:  E El-Fakahany; E Richelson
Journal:  Br J Pharmacol       Date:  1983-01       Impact factor: 8.739

10.  [3H]-Quinuclidinyl benzilate binding to muscarinic receptors in rat brain: comparison of results from intact brain slices and homogenates.

Authors:  R F Gilbert; M R Hanley; L L Iversen
Journal:  Br J Pharmacol       Date:  1979-03       Impact factor: 8.739
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.