Literature DB >> 5649891

Evidence that central nervous system depression by 1,4-butanediol in mediated through a metabolite, gamma-hydroxybutyrate.

R H Roth, N J Giarman.   

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Year:  1968        PMID： 5649891     DOI： 10.1016/0006-2952(68)90010-5

Source DB:  PubMed          Journal:  Biochem Pharmacol        ISSN： 0006-2952            Impact factor:   5.858


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  7 in total

1.  Hypnogenic properties of succinic semialdehyde and its fatty acid derivatives.

Authors:  G A Kerkut; P V Taberner
Journal:  Br J Pharmacol       Date:  1971-10       Impact factor: 8.739

2.  The effect of sodium -hydroxybutyrate on the metabolism of dopamine in the brain.

Authors:  D A Hutchins; K S Rayevsky; D F Sharman
Journal:  Br J Pharmacol       Date:  1972-11       Impact factor: 8.739

3.  Effects of 1,4-butanediol administration on oxidative stress in rat brain: study of the neurotoxicity of gamma-hydroxybutyric acid in vivo.

Authors:  Angela M Sgaravatti; Alessandra S Magnusson; Amanda S Oliveira; Caroline P Mescka; Fernanda Zanin; Mirian B Sgarbi; Carolina D Pederzolli; Angela T S Wyse; Clóvis M D Wannmacher; Moacir Wajner; Carlos S Dutra-Filho
Journal:  Metab Brain Dis       Date:  2009-03-19       Impact factor: 3.584

4.  Physical dependence on gamma-hydroxybutrate (GHB) prodrug 1,4-butanediol (1,4-BD): time course and severity of withdrawal in baboons.

Authors:  Amy K Goodwin; K Michael Gibson; Elise M Weerts
Journal:  Drug Alcohol Depend       Date:  2013-03-26       Impact factor: 4.492

5.  Pharmacological evidence for a selective antidopaminergic action of gamma-hydroxybutyric acid.

Authors:  K Menon; D Bieger; O Hornykiewicz
Journal:  J Neural Transm       Date:  1976       Impact factor: 3.575

Review 6.  Behavioral analyses of GHB: receptor mechanisms.

Authors:  Lawrence P Carter; Wouter Koek; Charles P France
Journal:  Pharmacol Ther       Date:  2008-10-29       Impact factor: 12.310

7.  Behavioral effects and pharmacokinetics of gamma-hydroxybutyrate (GHB) precursors gamma-butyrolactone (GBL) and 1,4-butanediol (1,4-BD) in baboons.

Authors:  A K Goodwin; P R Brown; E E W Jansen; C Jakobs; K M Gibson; E M Weerts
Journal:  Psychopharmacology (Berl)       Date:  2009-02-06       Impact factor: 4.530
  7 in total

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