Literature DB >> 563803

Modification of hepatotoxic effects of aflatoxin B1 in rabbits by immunization.

I Ueno, F S Chu.   

Abstract

Reduction of acute toxic effect of aflatoxin B1 was achieved by immunizing the rabbits with small amounts of bovine serum albumin-aflatoxin B1 conjugate. Rabbits after immunization showed lower mortality, near normal serum isocitric dehydrogenase activity, no abnormality in livers when challenged with a single dose of aflatoxin B1. The results suggest that immunization might be used prophylactically against aflatoxicosis.

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Year:  1978        PMID： 563803     DOI： 10.1007/bf01921918

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  6 in total

Review 1.  Mycotoxins.

Authors:  G N Wogan
Journal:  Annu Rev Pharmacol       Date:  1975       Impact factor: 13.820

2.  Preparation and characterization of aflatox-n B1-1-(O-carboxymethyl) oxime.

Authors:  F S Chu; M T Hsia; P S Sun
Journal:  J Assoc Off Anal Chem       Date:  1977-07

3.  Production of antibody against aflatoxin B1.

Authors:  F S Chu; I Ueno
Journal:  Appl Environ Microbiol       Date:  1977-05       Impact factor: 4.792

4.  Production of antibody against ochratoxin A.

Authors:  F S Chu; F C Chang; R D Hinsdill
Journal:  Appl Environ Microbiol       Date:  1976-06       Impact factor: 4.792

5.  Inhibition of chemically induced neoplasia by immunization with antigenic carcinogen-protein conjugate.

Authors:  R M Peck; E B Peck
Journal:  Cancer Res       Date:  1971-11       Impact factor: 12.701

6.  Aflatoxin B; specific antibodies and their use in radioimmunoassay.

Authors:  J J Langone; H Van Vunakis
Journal:  J Natl Cancer Inst       Date:  1976-03       Impact factor: 13.506
  6 in total
  2 in total

1.  Vaccination of lactating dairy cows for the prevention of aflatoxin B1 carry over in milk.

Authors:  Luciano Polonelli; Laura Giovati; Walter Magliani; Stefania Conti; Stefano Sforza; Alessandro Calabretta; Claudio Casoli; Paola Ronzi; Ester Grilli; Antonio Gallo; Francesco Masoero; Gianfranco Piva
Journal:  PLoS One       Date:  2011-10-28       Impact factor: 3.240

Review 2.  AFM₁ in Milk: Physical, Biological, and Prophylactic Methods to Mitigate Contamination.

Authors:  Laura Giovati; Walter Magliani; Tecla Ciociola; Claudia Santinoli; Stefania Conti; Luciano Polonelli
Journal:  Toxins (Basel)       Date:  2015-10-23       Impact factor: 4.546
  2 in total

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