| Literature DB >> 5634500 |
V G Allfrey, B G Pogo, V C Littau, E L Gershey, A E Mirsky.
Abstract
Acetylation of histones takes place along the salivary gland chromosomes of Chironomus thummi when RNA synthesis is active. It can be observed but not measured quantitatively by autoradiography of chromosome squashes. The "fixatives" commonly used in preparing squashes of insect chromosomes preferentially extract the highly acetylated "arginine-rich" histone fractions; the use of such fixatives may explain the reported absence of histone acetylation in Drosophila melanogaster.Entities:
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Year: 1968 PMID： 5634500 DOI： 10.1126/science.159.3812.314
Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728