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Literature DB >> 20110548

Modern approaches for investigating epigenetic signaling pathways.

Adam G Evertts¹, Barry M Zee, Benjamin A Garcia.

Abstract

Epigenetics is increasingly being recognized as a central component of physiological processes as diverse as obesity and circadian rhythms. Primarily acting through DNA methylation and histone posttranslational modifications, epigenetic pathways enable both short- and long-term transcriptional activation and silencing, independently of the underlying genetic sequence. To more quantitatively study the molecular basis of epigenetic regulation in physiological processes, the present review informs the latest techniques to identify and compare novel DNA methylation marks and combinatorial histone modifications across different experimental conditions, and to localize both DNA methylation and histone modifications over specific genomic regions.

Entities: Disease

Mesh：

Substances：
Histones

Year: 2010 PMID： 20110548 PMCID： PMC3774515 DOI： 10.1152/japplphysiol.00007.2010

Source DB: PubMed Journal: J Appl Physiol (1985) ISSN： 0161-7567

61 in total

1. ACETYLATION AND METHYLATION OF HISTONES AND THEIR POSSIBLE ROLE IN THE REGULATION OF RNA SYNTHESIS.

Authors: V G ALLFREY; R FAULKNER; A E MIRSKY
Journal: Proc Natl Acad Sci U S A Date: 1964-05 Impact factor: 11.205

2. Genomic maps and comparative analysis of histone modifications in human and mouse.

Authors: Bradley E Bernstein; Michael Kamal; Kerstin Lindblad-Toh; Stefan Bekiranov; Dione K Bailey; Dana J Huebert; Scott McMahon; Elinor K Karlsson; Edward J Kulbokas; Thomas R Gingeras; Stuart L Schreiber; Eric S Lander
Journal: Cell Date: 2005-01-28 Impact factor: 41.582

3. Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex.

Authors: X Nan; H H Ng; C A Johnson; C D Laherty; B M Turner; R N Eisenman; A Bird
Journal: Nature Date: 1998-05-28 Impact factor: 49.962

4. DNA (cytosine-5)-methyltransferases in mouse cells and tissues. Studies with a mechanism-based probe.

Authors: J A Yoder; N S Soman; G L Verdine; T H Bestor
Journal: J Mol Biol Date: 1997-07-18 Impact factor: 5.469

5. Dissection of the methyl-CpG binding domain from the chromosomal protein MeCP2.

Authors: X Nan; R R Meehan; A Bird
Journal: Nucleic Acids Res Date: 1993-10-25 Impact factor: 16.971

6. Circadian regulator CLOCK is a histone acetyltransferase.

Authors: Masao Doi; Jun Hirayama; Paolo Sassone-Corsi
Journal: Cell Date: 2006-05-05 Impact factor: 41.582

7. A rapid, sensitive method for detection of alkaline phosphatase-conjugated anti-antibody on Western blots.

Authors: M S Blake; K H Johnston; G J Russell-Jones; E C Gotschlich
Journal: Anal Biochem Date: 1984-01 Impact factor: 3.365

Review 8. Heterochromatin and gene expression in Drosophila.

Authors: K S Weiler; B T Wakimoto
Journal: Annu Rev Genet Date: 1995 Impact factor: 16.830

9. Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands.

Authors: J G Herman; J R Graff; S Myöhänen; B D Nelkin; S B Baylin
Journal: Proc Natl Acad Sci U S A Date: 1996-09-03 Impact factor: 11.205

10. High sensitivity mapping of methylated cytosines.

Authors: S J Clark; J Harrison; C L Paul; M Frommer
Journal: Nucleic Acids Res Date: 1994-08-11 Impact factor: 16.971

10 in total

Review 1. Proteomic investigation of epigenetics in neuropsychiatric disorders: a missing link between genetics and behavior?

Authors: Mariana D Plazas-Mayorca; Kent E Vrana
Journal: J Proteome Res Date: 2010-09-09 Impact factor: 4.466

Review 2. Analytical tools and current challenges in the modern era of neuroepigenomics.

Authors: Ian Maze; Li Shen; Bin Zhang; Benjamin A Garcia; Ningyi Shao; Amanda Mitchell; HaoSheng Sun; Schahram Akbarian; C David Allis; Eric J Nestler
Journal: Nat Neurosci Date: 2014-10-28 Impact factor: 24.884

3. 6-n-propylthiouracil taster status not related to reported cruciferous vegetable intake among ethnically diverse children.

Authors: Tom Baranowski; Janice C Baranowski; Kathleen B Watson; Russell Jago; Noemi Islam; Alicia Beltran; Shelby J Martin; Nga Nguyen; Beverly J Tepper
Journal: Nutr Res Date: 2011-08-05 Impact factor: 3.315

Review 4. Nutrition, epigenetics, and metabolic syndrome.

Authors: Junjun Wang; Zhenlong Wu; Defa Li; Ning Li; Scott V Dindot; M Carey Satterfield; Fuller W Bazer; Guoyao Wu
Journal: Antioxid Redox Signal Date: 2012-01-13 Impact factor: 8.401

Review 5. Molecular genomic research designs.

Authors: Kelley Baumgartel; Jamie Zelazny; Theresa Timcheck; Chantel Snyder; Mandy Bell; Yvette P Conley
Journal: Annu Rev Nurs Res Date: 2011