Literature DB >> 5621470

Nature of hamster complement-fixing antibody to adenovirus 12 tumor antigen.

R A Fugmann, M M Sigel.   

Abstract

The presence of complement-fixing (CF) antibody reactive with T antigen and with viral C antigen in hamsters bearing adenovirus 12-induced tumors has been confirmed. Antibody activity in serum obtained at a time when the host was bearing large tumors was found to be associated exclusively with 7S immunoglobulins. Two populations of 7S immunoglobulins showing CF reactivity were distinguished by electrical charge, as determined by diethylaminoethyl cellulose chromatography and immunoelectrophoresis. No antibodies of the 19S IgM type were detected in the serum of hamsters bearing large tumors.

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Year:  1967        PMID: 5621470      PMCID: PMC375336     

Source DB:  PubMed          Journal:  J Virol        ISSN: 0022-538X            Impact factor:   5.103


  14 in total

1.  Study of adenovirus antigens by immunoelectrophoresis.

Authors:  H G PEREIRA; A C ALLISON; C P FARTHING
Journal:  Nature       Date:  1959-03-28       Impact factor: 49.962

2.  Application of a microtechnique to viral serological investigations.

Authors:  J L SEVER
Journal:  J Immunol       Date:  1962-03       Impact factor: 5.422

3.  Purification and immunological characterization of types 4 and 5 adenovirus-soluble antigens.

Authors:  W C WILCOX; H S GINSBERG
Journal:  Proc Natl Acad Sci U S A       Date:  1961-04-15       Impact factor: 11.205

4.  Competition between, and effectiveness of, IgG and IgM antibodies in indirect fluorescent antibody and other tests.

Authors:  I R Cohen; L C Norins; A J Julian
Journal:  J Immunol       Date:  1967-01       Impact factor: 5.422

5.  Complement fixation on cell surfaces by 19S and 7S antibodies.

Authors:  T Borsos; H J Rapp
Journal:  Science       Date:  1965-10-22       Impact factor: 47.728

6.  Methods for the separation, purification and measurement of nine components of hemolytic complement in guinea-pig serum.

Authors:  R A Nelson; J Jensen; I Gigli; N Tamura
Journal:  Immunochemistry       Date:  1966-03

7.  Adenovirus antibody and antibody to 'T' antigen (neoantigen) location in gamma-globulin.

Authors:  A C Hollinshead; T C Alford; H C Turner; R J Huebner
Journal:  Nature       Date:  1966-07-23       Impact factor: 49.962

8.  Adenovirus antibody measured by the passive hemagglutination test.

Authors:  S S Lefkowitz; J A Williams; B E Howard; M M Sigel
Journal:  J Bacteriol       Date:  1966-01       Impact factor: 3.490

9.  Properties of guinea pig 7S antibodies. I. Electrophoretic separation of two types of guinea pig 7S antibodies.

Authors:  B BENACERRAF; Z OVARY; K J BLOCH; E C FRANKLIN
Journal:  J Exp Med       Date:  1963-06-01       Impact factor: 14.307

10.  THE IMMUNOGLOBULINS OF MICE. I. FOUR MAJOR CLASSES OF IMMUNOGLOBULINS: 7S GAMMA-2-, 7S GAMMA-1-, GAMMA-1A (BETA-2A)-, AND 18S GAMMA-1M-GLOBULINS.

Authors:  J L FAHEY; J WUNDERLICH; R MISHELL
Journal:  J Exp Med       Date:  1964-08-01       Impact factor: 14.307

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  1 in total

1.  Separation of two components of adenovirus type 12 induced T-antigens with sephadex G-50.

Authors:  P Erb; M Gasser; H Loeffler
Journal:  Experientia       Date:  1968-12-15
  1 in total

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