| Literature DB >> 561159 |
Abstract
Homozygous mouse blastocysts have been produced following microsurgical removal of one pronucleus from the fertilized egg, diploidization in cytochalasin B, and culture in vitro. This combination of techniques should greatly shorten the time required to obtain homozygous strains of mice.Entities:
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Year: 1977 PMID: 561159 DOI: 10.1002/jez.1402010213
Source DB: PubMed Journal: J Exp Zool ISSN: 0022-104X