Literature DB >> 561065

Calcium-sensitivity of the microtubule reassembly system. Difference between crude brain extract and purified microtubular proteins.

E Nishida, H Sakai.   

Abstract

Microtubule reassembly in crude extracts of porcine brain was inhibited by 10(-5) M Ca2+, wherease 10(-3) M Ca2+ was required for inhibition of the reassembly from purified microtubular proteins. This accounts for the apparent discrepancies between the results reported by other investigators. Furthermore, the Ca-sensitivity of the purified microtubular proteins was nearly completely recovered on addition of a fraction obtained from crude brain extract.

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Year:  1977        PMID: 561065     DOI: 10.1093/oxfordjournals.jbchem.a131685

Source DB:  PubMed          Journal:  J Biochem        ISSN: 0021-924X            Impact factor:   3.387


  8 in total

1.  Rotavirus infection induces cytoskeleton disorganization in human intestinal epithelial cells: implication of an increase in intracellular calcium concentration.

Authors:  J P Brunet; N Jourdan; J Cotte-Laffitte; C Linxe; M Géniteau-Legendre; A Servin; A M Quéro
Journal:  J Virol       Date:  2000-11       Impact factor: 5.103

2.  Intracellular free calcium levels are reduced in mitotic Pt K2 epithelial cells.

Authors:  C H Keith; F R Maxfield; M L Shelanski
Journal:  Proc Natl Acad Sci U S A       Date:  1985-02       Impact factor: 11.205

3.  Calcium lability of cytoplasmic microtubules and its modulation by microtubule-associated proteins.

Authors:  M Schliwa; U Euteneuer; J C Bulinski; J G Izant
Journal:  Proc Natl Acad Sci U S A       Date:  1981-02       Impact factor: 11.205

4.  Rapid disassembly of cold-stable microtubules by calmodulin.

Authors:  D Job; E H Fischer; R L Margolis
Journal:  Proc Natl Acad Sci U S A       Date:  1981-08       Impact factor: 11.205

5.  Characterization of the interaction of TZT-1027, a potent antitumor agent, with tubulin.

Authors:  T Natsume; J Watanabe; S Tamaoki; N Fujio; K Miyasaka; M Kobayashi
Journal:  Jpn J Cancer Res       Date:  2000-07

Review 6.  EFA6 in Axon Regeneration, as a Microtubule Regulator and as a Guanine Nucleotide Exchange Factor.

Authors:  Gilberto Gonzalez; Lizhen Chen
Journal:  Cells       Date:  2021-05-26       Impact factor: 6.600

7.  Calmodulin-microtubule association in cultured mammalian cells.

Authors:  W J Deery; A R Means; B R Brinkley
Journal:  J Cell Biol       Date:  1984-03       Impact factor: 10.539

8.  Strongylocentrotus purpuratus spindle tubulin. II. Characteristics of its sensitivity to Ca++ and the effects of calmodulin isolated from bovine brain and S. purpuratus eggs.

Authors:  T C Keller; D K Jemiolo; W H Burgess; L I Rebhun
Journal:  J Cell Biol       Date:  1982-06       Impact factor: 10.539

  8 in total

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