Use of the 'Analmatic clinical system' in the microbiological assay of vitamin B 12 and folic acid in serum.

The routine estimation of large numbers of serum folic acid and vitamin B(12) levels using the Baird and Tatlock(1) Analmatic clinical system is described and the method evaluated.Precision, accuracy, and carryover are shown to be at acceptable levels, and the advantages and disadvantages of the use of the system are discussed. It is considered that with some modifications the Analmatic system offers a reliable and labour-saving method of carrying out considerable numbers of routine microbiological assays.