Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Stimulating action of catecholamines on isolated preparations of the rat colon and human and rabbit taeniae coli.

Literature DB >> 5572281

Stimulating action of catecholamines on isolated preparations of the rat colon and human and rabbit taeniae coli.

Abstract

1. Adrenaline and noradrenaline induced dose related relaxations of the superfused rat colon. The relaxations were progressively transformed into contractions when beta-adrenoceptors were blocked with increasing doses of oxprenolol.2. Since phentolamine or phenoxybenzamine inhibited the contractions induced by adrenaline or noradrenaline in the presence of oxprenolol, it is assumed that the contractions are caused by stimulation of excitatory alpha-adrenoceptors.3. Human and rabbit taeniae coli showed responses that were qualitatively similar to those observed with the rat colon.

Entities: Chemical Disease Species

Mesh：

Substances：

Year: 1971 PMID： 5572281 PMCID： PMC1703254 DOI： 10.1111/j.1476-5381.1971.tb08037.x

Source DB: PubMed Journal: Br J Pharmacol ISSN： 0007-1188 Impact factor: 8.739

12 in total

9. Intestinal smooth muscles: demonstration of catecholamines-induced contraction mediated through alpha-adrenergic receptors.

Authors: D J Gagon
Journal: Eur J Pharmacol Date: 1970-05 Impact factor: 4.432

Stimulating action of catecholamines on isolated preparations of the rat colon and human and rabbit taeniae coli.

1. A SENSITIVE METHOD FOR THE ASSAY OF ANGIOTENSIN.

2. Andrenergic receptive mechanism of canine ileum.

3. The estimation of adrenaline and allied substances in blood.

4. Sympathetic receptor action.

5. The effect of adrenaline on the guinea-pig intestine.

6. The pharmacologic action of some analogs of 1-(3,4-dihydroxyphenyl)-2-amino-1-butanol (ethylnorepinephrine).

7. Alpha excitatory, alpha inhibitory and beta inhibitory adrenergic receptors in the guinea-pig stomach.

8. Some effects of sympathomimetic amines on isolated smooth muscle preparations from the stomach of the guinea-pig.

9. Intestinal smooth muscles: demonstration of catecholamines-induced contraction mediated through alpha-adrenergic receptors.

10. A PRELIMINARY INVESTIGATION OF THE PHARMACOLOGY OF THE HUMAN ISOLATED TAENIA COLI PREPARATION.

Review 1. Symposium on colonic function. Electrophysiology of the colon.

2. Excitatory effects of adrenaline upon isolated preparations of human colon.

3. The rat isolated colon as a specific assay organ for angiotensin.

4. Specific antagonists for the myotropic action of angiotensin II and angiotensin I on the isolated rat colon.