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Literature DB >> 14228135

A SENSITIVE METHOD FOR THE ASSAY OF ANGIOTENSIN.

Abstract

A method is described for the assay of angiotensin on the rat colon. Under the conditions of the assay, the preparation is sensitive to angiotensin and relatively insensitive to 5-hydroxytryptamine, to histamine and to other substances which might be present in blood. Bradykinin and catechol amines do not interfere with the assay. Evidence is given for the specificity of the angiotensin receptors.

Entities: Chemical Species

Keywords: ANGIOTENSIN; BIOLOGICAL ASSAY; BRADYKININ; CATECHOLAMINES; COLON; EXPERIMENTAL LAB STUDY; HISTAMINE; MUSCLE, SMOOTH; RATS; RECEPTORS, NEURAL; SEROTONIN

Mesh：

Substances：

Year: 1964 PMID： 14228135 PMCID： PMC1704097 DOI： 10.1111/j.1476-5381.1964.tb01591.x

Source DB: PubMed Journal: Br J Pharmacol Chemother ISSN： 0366-0826

17 in total

1. THE ACTION OF PEPTIDES ON THE ADRENAL MEDULLA. RELEASE OF ADRENALINE BY BRADYKININ AND ANGIOTENSIN.

Authors: W FELDBERG; G P LEWIS
Journal: J Physiol Date: 1964-05 Impact factor: 5.182

2. Further studies on the preparation, purification and nature of irin.

Authors: N AMBACHE
Journal: J Physiol Date: 1959-05-19 Impact factor: 5.182

3. A pendulum auxotonic lever.

Authors: W D PATON
Journal: J Physiol Date: 1957-07-11 Impact factor: 5.182

4. Observations concerning the unitage system and sensitivity of some biological preparations to hypertension.

Authors: J L PRADO; J R VALLE; Z P PICARELLI
Journal: Acta Physiol Lat Am Date: 1954

5. Bioassay of hypertensin in pithed rats and cats based on a four-point design.

Authors: J R VALLE; E S PRADO; J L PRADO
Journal: Acta Physiol Lat Am Date: 1952-12

6. A method of assaying small amounts of hypertensin.

Authors: L T SKEGGS; J R KAHN; W H MARSH
Journal: Lab Invest Date: 1953 Mar-Apr Impact factor: 5.662

7. Fractionation of the smooth muscle stimulants present in extracts of gastro-intestinal tract. Identification of 5-hydroxytryptamine and its distinction from substance P.

Authors: C E DALGLIESH; C C TOH; T S WORK
Journal: J Physiol Date: 1953-05-28 Impact factor: 5.182

8. The estimation of adrenaline and allied substances in blood.

Authors: J H Gaddum; W S Peart; M Vogt
Journal: J Physiol Date: 1949-06-15 Impact factor: 5.182

9. A spectrum of pharmacological activity in some biologically active peptides.

Authors: G W BISSET; G P LEWIS
Journal: Br J Pharmacol Chemother Date: 1962-08

10. A sensitive method for the assay of 5-hydroxytryptamine.

Authors: J R VANE
Journal: Br J Pharmacol Chemother Date: 1957-09

66 in total

1. A further investigation into the energy dependence of angiotensin II-induced contractions of isolated smooth muscle preparations.

Authors: A D Crocker; K A Wilson
Journal: Br J Pharmacol Date: 1975-01 Impact factor: 8.739

A SENSITIVE METHOD FOR THE ASSAY OF ANGIOTENSIN.

1. THE ACTION OF PEPTIDES ON THE ADRENAL MEDULLA. RELEASE OF ADRENALINE BY BRADYKININ AND ANGIOTENSIN.

2. Further studies on the preparation, purification and nature of irin.

3. A pendulum auxotonic lever.

4. Observations concerning the unitage system and sensitivity of some biological preparations to hypertension.

5. Bioassay of hypertensin in pithed rats and cats based on a four-point design.

6. A method of assaying small amounts of hypertensin.

7. Fractionation of the smooth muscle stimulants present in extracts of gastro-intestinal tract. Identification of 5-hydroxytryptamine and its distinction from substance P.

8. The estimation of adrenaline and allied substances in blood.

9. A spectrum of pharmacological activity in some biologically active peptides.

10. A sensitive method for the assay of 5-hydroxytryptamine.

1. A further investigation into the energy dependence of angiotensin II-induced contractions of isolated smooth muscle preparations.

2. Gas exchange of single red blood cells within secondary lamellae of fish gills.

3. Prostaglandins and the mechanism of analgesia produced by aspirin-like drugs. 1973.

4. The rat isolated colon as a specific assay organ for angiotensin.

5. Acceleration of catecholamine biosynthesis in sympathetically innervated tissues by angiotensin-II-amide..

6. Mechanism of noradrenaline potentiation by prostaglandin E2 in rat mesenteric artery.

7. Angiotensin II-like activity in circulating arterial blood in immature and adult rabbits.

8. Adrenoceptors and regulation of intestinal tone in the isolated colon of the mouse.

9. Release of vasopressin from the rat hypothalamo-neurohypophysial system by angiotensin-(1-7) heptapeptide.

10. Bradykinin and functional vasodilatation in the salivary gland.