Literature DB >> 5571308

Uptake and release of 14 C-5-hydroxytryptamine by platelets in affective illness.

D M Shaw, D A MacSweeney, N Woolcock, A B Bevan-Jones.   

Abstract

In the search for paradigms of postulated abnormalities in indolamine function in the brain in affective disorders, 5-HT uptake and release was estimated in platelets from patients suffering from severe depressive illness. Neither of these measures was altered by the illness and the most likely explanation for the negative findings was that in this setting platelets are not a suitable model.

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Year:  1971        PMID: 5571308      PMCID: PMC1083455          DOI: 10.1136/jnnp.34.3.224

Source DB:  PubMed          Journal:  J Neurol Neurosurg Psychiatry        ISSN: 0022-3050            Impact factor:   10.154


  2 in total

Review 1.  Metabolism, transfer and storage of 5-hydroxytryptamine in blood platelets.

Authors:  A Pletscher
Journal:  Br J Pharmacol Chemother       Date:  1968-01

2.  Tryptamine metabolism in depression.

Authors:  A Coppen; D M Shaw; A Malleson; E Eccleston; G Gundy
Journal:  Br J Psychiatry       Date:  1965-10       Impact factor: 9.319

  2 in total
  9 in total

1.  5-Hydroxytryptamine (5-HT) in the whole-blood of patients with depressive illness.

Authors:  A Coppen; P Turner; A R Rowsell; C Padgham
Journal:  Postgrad Med J       Date:  1976-03       Impact factor: 2.401

Review 2.  Biochemical assessment of antidepressive drugs.

Authors:  K Ghose
Journal:  Br J Clin Pharmacol       Date:  1980-12       Impact factor: 4.335

3.  Decreased uptake of 5-hydroxytryptamine in blood platelets from patients with endogenous depression.

Authors:  J Tuomisto; E Tukiainen; U G Ahlfors
Journal:  Psychopharmacology (Berl)       Date:  1979-10       Impact factor: 4.530

4.  The content and uptake of 5-HT by blood platelets in depressive patients.

Authors:  G F Oxenkrug
Journal:  J Neural Transm       Date:  1979       Impact factor: 3.575

5.  Ect and platelet 5ht uptake in major depression.

Authors:  P K Dalal; N Lal; J K Trivedi; P K Seth; A K Agarwal; A Khalid
Journal:  Indian J Psychiatry       Date:  1997-10       Impact factor: 1.759

6.  Active platelet 5-ht uptake in depressives treated with impramine and ect.

Authors:  P K Dalal; N Lal; J K Trivedi; P K Seth; A K Agarwal; A Khalid
Journal:  Indian J Psychiatry       Date:  1998-01       Impact factor: 1.759

7.  Effect of mianserin hydrochloride on peripheral uptake mechanisms for noradrenaline and 5-hydroxytryptamine in man.

Authors:  A Coppen; K Ghose; C Swade; K Wood
Journal:  Br J Clin Pharmacol       Date:  1978       Impact factor: 4.335

8.  Serotonin transporter genotype and function in relation to antidepressant response in Koreans.

Authors:  Woojae Myung; Shinn-Won Lim; Seonwoo Kim; Hyeran Kim; Jae Won Chung; Min Young Seo; Jong-Won Kim; Bernard J Carroll; Doh Kwan Kim
Journal:  Psychopharmacology (Berl)       Date:  2012-08-12       Impact factor: 4.530

9.  3H-imipramine binding and serotonin uptake in platelets from untreated depressed patients and control volunteers.

Authors:  R Raisman; M S Briley; F Bouchami; D Sechter; E Zarifian; S Z Langer
Journal:  Psychopharmacology (Berl)       Date:  1982       Impact factor: 4.530

  9 in total

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