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Literature DB >> 556923

Microassay foramphotericin B.

Abstract

Depending on the hematocrit, duplicate or triplicate determinations of serum amphotericin B concentration may be made on as little as 100 mul of capillary blood obtained by finger prick. In an accurate plate diffusion bioassay, using Paecilomyces varioti as the indicator organism, levels of the drug in the therapeutic range can be determined fast enough for clinicians to modify their next dose.

Entities: Chemical

Mesh：

Substances：
Amphotericin B

Year: 1977 PMID： 556923 PMCID： PMC351916 DOI： 10.1128/AAC.11.1.44

Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.191

2 in total

1. Bioassay for hamycin and amphotericin B in serum and other biological fluids.

Authors: S Shadomy; J A McCay; S I Schwartz
Journal: Appl Microbiol Date: 1969-04

2. Amphotericin B serum concentrations during therapy.

Authors: B T Fields; J H Bates; R S Abernathy
Journal: Appl Microbiol Date: 1970-06

2 in total

9 in total

1. Efficacy of cilofungin therapy administered by continuous intravenous infusion for experimental disseminated candidiasis in rabbits.

Authors: M S Rouse; B M Tallan; J M Steckelberg; N K Henry; W R Wilson
Journal: Antimicrob Agents Chemother Date: 1992-01 Impact factor: 5.191

2. A sensitive amphotericin B immunoassay for pharmacokinetic and distribution studies.

Authors: S Machard; F Theodoro; H Benech; J M Grognet; E Ezan
Journal: Antimicrob Agents Chemother Date: 2000-03 Impact factor: 5.191

3. Rapid determination of amphotericin B levels in serum by high-performance liquid chromatography without interference by bilirubin.

Authors: H Hosotsubo; J Takezawa; N Taenaka; K Hosotsubo; I Yoshiya
Journal: Antimicrob Agents Chemother Date: 1988-07 Impact factor: 5.191

Microassay foramphotericin B.

1. Bioassay for hamycin and amphotericin B in serum and other biological fluids.

2. Amphotericin B serum concentrations during therapy.

1. Efficacy of cilofungin therapy administered by continuous intravenous infusion for experimental disseminated candidiasis in rabbits.

2. A sensitive amphotericin B immunoassay for pharmacokinetic and distribution studies.

3. Rapid determination of amphotericin B levels in serum by high-performance liquid chromatography without interference by bilirubin.

4. Evaluation of a murine model of hepatic candidiasis.

Review 5. Clinical pharmacokinetics of systemic antifungal drugs.

6. Discrepant results of amphotericin B assays on fresh versus frozen serum samples.

7. Effect of fasting on temporal variation in the nephrotoxicity of amphotericin B in rats.

8. Chloramphenicol bioassay.

9. Sensitive high-pressure liquid chromatographic assay for amphotericin B which incorporates an internal standard.