Literature DB >> 3190197

Rapid determination of amphotericin B levels in serum by high-performance liquid chromatography without interference by bilirubin.

H Hosotsubo1, J Takezawa, N Taenaka, K Hosotsubo, I Yoshiya.   

Abstract

A high-performance liquid chromatographic method for the determination of amphotericin B concentrations in human serum without bilirubin interference was developed and compared with a microbiological assay. The high-performance liquid chromatographic assay utilized a reversed-phase trimethyl silica column, simple sample preparation, and visible detection. Reproducibility studies yielded coefficient-of-variation ranges from 1.02 to 2.11% for within-day precision and 2.88 to 4.32% for between-day precision. The correlation coefficient with the microbiological assay was 0.984 for amphotericin B.

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Year:  1988        PMID： 3190197      PMCID： PMC172355          DOI： 10.1128/AAC.32.7.1103

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  11 in total

1.  Amphotericin B toxicity. A follow-up report of 53 patients.

Authors:  R P Miller; J H Bates
Journal:  Ann Intern Med       Date:  1969-12       Impact factor: 25.391

2.  Reproducible measurement of amphotericin B in serum by high-performance liquid chromatography in alkaline buffer.

Authors:  M Leclercq; M Fouillit; G Panteix; R Guinet
Journal:  J Chromatogr       Date:  1985-02-08

3.  Microassay foramphotericin B.

Authors:  R M Bannatyne; R Cheung; H R Devlin
Journal:  Antimicrob Agents Chemother       Date:  1977-01       Impact factor: 5.191

4.  Measurement of amphotericin B in serum or plasma by high-performance liquid chromatography.

Authors:  C L Golas; C G Prober; S M MacLeod; S J Soldin
Journal:  J Chromatogr       Date:  1983-12-09

5.  Quantitative extraction of amphotericin B from serum and its determination by high-pressure liquid chromatography.

Authors:  P R Bach
Journal:  Antimicrob Agents Chemother       Date:  1984-09       Impact factor: 5.191

6.  An internally-standardized assay for amphotericin B in tissues and plasma.

Authors:  J W Mayhew; C Fiore; T Murray; M Barza
Journal:  J Chromatogr       Date:  1983-05-13

Review 7.  Antifungal agents used in systemic mycoses. Activity and therapeutic use.

Authors:  J R Graybill; P C Craven
Journal:  Drugs       Date:  1983-01       Impact factor: 9.546

8.  Bioassay for hamycin and amphotericin B in serum and other biological fluids.

Authors:  S Shadomy; J A McCay; S I Schwartz
Journal:  Appl Microbiol       Date:  1969-04

9.  Sensitive high-pressure liquid chromatographic assay for amphotericin B which incorporates an internal standard.

Authors:  G G Granich; G S Kobayashi; D J Krogstad
Journal:  Antimicrob Agents Chemother       Date:  1986-04       Impact factor: 5.191

10.  Quantitation of amphotericin B with use of high-pressure liquid chromatography.

Authors:  I Nilsson-Ehle; T T Yoshikawa; J E Edwards; M C Schotz; L B Guze
Journal:  J Infect Dis       Date:  1977-03       Impact factor: 5.226
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  1 in total

1.  Flow cytometric assay for estimating fungicidal activity of amphotericin B in human serum.

Authors:  E Martin; U Schlasius; S Bhakdi
Journal:  Med Microbiol Immunol       Date:  1992       Impact factor: 3.402
  1 in total

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