Literature DB >> 555577

Predicting phenytoin dose - a revised nomogram.

B Rambeck, H E Boenigk, A Dunlop, P W Mullen, J Wadsworth, A Richens.   

Abstract

The nomogram devised by Richens and Dunlop for predicting phenytoin dose has been tested in 127 residential epileptic patients, and the data obtained were used to prepare a revised version of the nomogram. In a further 78 patients, this new version was found to be superior to the original. The mean Km value was found to be 23.8 mumoles/liter. Km was independent of age and body surface area, but Dmax correlated positively with the latter two variables.

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Year:  1979        PMID： 555577     DOI： 10.1097/00007691-197901030-00007

Source DB:  PubMed          Journal:  Ther Drug Monit        ISSN： 0163-4356            Impact factor:   3.681


  20 in total

Review 1.  Therapeutic drug monitoring of phenytoin. Rationale and current status.

Authors:  M Levine; T Chang
Journal:  Clin Pharmacokinet       Date:  1990-11       Impact factor: 6.447

Review 2.  Bayesian parameter estimation and population pharmacokinetics.

Authors:  A H Thomson; B Whiting
Journal:  Clin Pharmacokinet       Date:  1992-06       Impact factor: 6.447

3.  High-dose melphalan dosage adjustment: possibility of using a test-dose.

Authors:  B Tranchand; Y D Ploin; M P Minuit; C Sapet; P Biron; T Philip; C Ardiet
Journal:  Cancer Chemother Pharmacol       Date:  1989       Impact factor: 3.333

4.  Clinical application of the Mullen and Foster method for individualizing phenytoin dosage.

Authors:  T Valenza; A Messori; G Zaccara; G Arnetoli; C Bartoli; G Donati-Cori; G C Muscas; R Silvano; E Tendi; R Zappoli
Journal:  Ital J Neurol Sci       Date:  1984-06

5.  Management of refractory complex partial seizures: current state of the art.

Authors:  David M Treiman
Journal:  Neuropsychiatr Dis Treat       Date:  2010-06-24       Impact factor: 2.570

6.  Steady-state pharmacokinetics of phenytoin from routinely collected patient data.

Authors:  T H Grasela; L B Sheiner; B Rambeck; H E Boenigk; A Dunlop; P W Mullen; J Wadsworth; A Richens; T Ishizaki; K Chiba
Journal:  Clin Pharmacokinet       Date:  1983 Jul-Aug       Impact factor: 6.447

7.  Phenytoin dosage predictions in paediatric patients.

Authors:  G J Yuen; P T Latimer; L C Littlefield; R W Mackey
Journal:  Clin Pharmacokinet       Date:  1989-04       Impact factor: 6.447

Review 8.  Optimisation of antiepileptic drug therapy. The importance of serum drug concentration monitoring.

Authors:  E Yukawa
Journal:  Clin Pharmacokinet       Date:  1996-08       Impact factor: 6.447

Review 9.  An updated comparison of drug dosing methods. Part I: Phenytoin.

Authors:  R D Pryka; K A Rodvold; S M Erdman
Journal:  Clin Pharmacokinet       Date:  1991-03       Impact factor: 6.447

10.  Phenytoin Michaelis-Menten pharmacokinetics in Caucasian paediatric patients.

Authors:  L A Bauer; R A Blouin
Journal:  Clin Pharmacokinet       Date:  1983 Nov-Dec       Impact factor: 6.447
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