Literature DB >> 5548707

Insulin and microtubules in rat adipocytes.

D Soifer, T Braun, O Hechter.   

Abstract

Insulin appears to promote microtubule assemblty in rat adipocytes. Neithler oxytocin nor high concentrations of glucose has this effect. Colchicine inihibits stimulation by insulin of lipid and glycogen synthesis without influencing stimulation by insulin of glucose oxidation. The anabolic effects of oxytocin or high concentrations of glucose are not inhibited by colchicine. The "directive effect" of insulin may involve microtubules.

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Year:  1971        PMID： 5548707     DOI： 10.1126/science.172.3980.269

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  7 in total

1.  Ultrastructural localization of insulin receptors on adipocytes.

Authors:  L Jarett; R M Smith
Journal:  Proc Natl Acad Sci U S A       Date:  1975-09       Impact factor: 11.205

2.  Fat mobilization and ultrastructural changes in the peritoneal fat body of the lizard, Klauberina riversiana, in response to long photoperiod and exogenase estrone or progesterone.

Authors:  J L LaPointe; E M Rodríguez
Journal:  Cell Tissue Res       Date:  1974       Impact factor: 5.249

3.  Stimulation by insulin of cell elongation and microtubule assembly in embryonic chick-lens epithelia.

Authors:  J Piatigorsky; S S Rothschild; M Wollberg
Journal:  Proc Natl Acad Sci U S A       Date:  1973-04       Impact factor: 11.205

4.  Colchicine inhibition of the heparin-stimulated release of clearing-factor lipase from isolated fat-cells.

Authors:  A Cryer; A McDonald; E R Williams; D S Robinson
Journal:  Biochem J       Date:  1975-12       Impact factor: 3.857

5.  Role for the microtubule cytoskeleton in GLUT4 vesicle trafficking and in the regulation of insulin-stimulated glucose uptake.

Authors:  L M Fletcher; G I Welsh; P B Oatey; J M Tavaré
Journal:  Biochem J       Date:  2000-12-01       Impact factor: 3.857

Review 6.  Microtubules in insulin action: what's on the tube?

Authors:  Skylar R Batty; Paul R Langlais
Journal:  Trends Endocrinol Metab       Date:  2021-08-27       Impact factor: 10.586

7.  Effects of cytochalasin B, colchicine and vincristine on the metabolism of isolated fat-cells.

Authors:  E G Loten; B Jeanrenaud
Journal:  Biochem J       Date:  1974-05       Impact factor: 3.857
  7 in total

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