Literature DB >> 5547758

Effect of aminoguanidine, chlorpromazine and NSD-1055 on gastric secretion and ulceration in the Shay rat.

A G Radwan, G B West.   

Abstract

Both chlorpromazine and NSD-1055 (a non-steroidal anti-inflammatory drug) markedly lower the volume and acidity of gastric contents of rats subjected to pyloric ligation (Shay technique) and reduce the degree of ulceration in the stomach. On the other hand, aminoguanidine (an inhibitor of histaminase) has no effect on acid secretion or ulceration in these animals.

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Year:  1971        PMID: 5547758      PMCID: PMC1702748          DOI: 10.1111/j.1476-5381.1971.tb09946.x

Source DB:  PubMed          Journal:  Br J Pharmacol        ISSN: 0007-1188            Impact factor:   8.739


  10 in total

1.  MOBILIZATION AND FORMATION OF HISTAMINE IN THE GASTRIC MUCOSA AS RELATED TO ACID SECRETION.

Authors:  G KAHLSON; E ROSENGREN; D SVAHN; R THUNBERG
Journal:  J Physiol       Date:  1964-11       Impact factor: 5.182

2.  The distribution and properties of a histamine-methylating enzyme.

Authors:  D D BROWN; R TOMCHICK; J AXELROD
Journal:  J Biol Chem       Date:  1959-11       Impact factor: 5.157

3.  Physiology and pharmacology of vomiting.

Authors:  H L BORISON; S C WANG
Journal:  Pharmacol Rev       Date:  1953-06       Impact factor: 25.468

4.  Aromatic L-amino acid decarboxylase.

Authors:  W LOVENBERG; H WEISSBACH; S UDENFRIEND
Journal:  J Biol Chem       Date:  1962-01       Impact factor: 5.157

5.  A study of gastric secretion in fasting rats.

Authors:  D E DONALD; C F CODE
Journal:  Gastroenterology       Date:  1952-02       Impact factor: 22.682

6.  A critical study of the Shay rat.

Authors:  R J MADDEN; H H RAMSBURG; J M HUNDLEY
Journal:  Gastroenterology       Date:  1951-05       Impact factor: 22.682

7.  Relationship of histamine to gastrin and other secretagogues.

Authors:  B J Haverback; M I Stubrin; B J Dyce
Journal:  Fed Proc       Date:  1965 Nov-Dec

Review 8.  Histamine and gastric secretion: a later look, 1955-1965.

Authors:  C F Code
Journal:  Fed Proc       Date:  1965 Nov-Dec

9.  Release of histamine from stomach by vagus-stimulating drugs: association with gastric acid secretion.

Authors:  P A Shore
Journal:  Fed Proc       Date:  1965 Nov-Dec

10.  EFFECTS OF CHLORPROMAZINE AND BROMOLYSERGIC ACID DIETHYLAMIDE ON GASTRIC SECRETION OF ACID INDUCED BY HISTAMINE IN RATS.

Authors:  B O AMURE; M GINSBURG
Journal:  Br J Pharmacol Chemother       Date:  1964-06
  10 in total
  2 in total

1.  Effect of SAS (a new 10-N-acylaminophenothiazine) on gastric secretion and ulceration in rats.

Authors:  A Kumar; H L Sharma; V N Sharma
Journal:  Br J Pharmacol       Date:  1976-04       Impact factor: 8.739

2.  Induction of gastric histamine synthesis by H2-receptor antagonists: potentiation of their antisecretory activity by histidine decarboxylase inhibitors.

Authors:  Z Huszti; K Pik; R Frenkl
Journal:  Agents Actions       Date:  1980-09
  2 in total

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