Literature DB >> 5544876

Narcotic tolerance and dependence: lack of relationship with serotonin turnover in the brain.

D L Cheney, A Goldstein, S Algeri, E Costa.   

Abstract

Serotonin turnover was measured in mouse brain by means of the conversion of radioactivity from labeled tryptophan into serotonin. Animals with a high degree of tolerance to and physical dependence on morphine did not differ from control mice.

Entities:  

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Year:  1971        PMID： 5544876     DOI： 10.1126/science.171.3976.1169

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  5 in total

1.  Cellular biochemistry of narcotic analgesic drugs in the central nervous system of the rat.

Authors:  D H Clouet
Journal:  Psychiatr Q       Date:  1972

2.  Automatic recording of the abstinence syndrome in opioid-dependent mice.

Authors:  A Cowan; P Cowan
Journal:  Experientia       Date:  1972-09-15

3.  The synthesis rate and turnover time of 5-hydroxy-tryptamine in brains of rats treated chronically with morphine.

Authors:  H N Bhargava
Journal:  Br J Pharmacol       Date:  1979-02       Impact factor: 8.739

4.  Rapid accumulation of H3-serotonin in brains of rats receiving intraperitoneal H3-tryptophan: effects of 5,6-dihydroxytryptamine or female sex hormones.

Authors:  M T Hyyppä; D P Cardinali; H G Baumgarten; R J Wurtman
Journal:  J Neural Transm       Date:  1973       Impact factor: 3.575

5.  Decreased morphine intake by opiate addicted rats administered zimelidine, a 5-HT uptake inhibitor.

Authors:  L Rönnbäck; J Zeuchner; L Rosengren; A Wronski; S O Ogren
Journal:  Psychopharmacology (Berl)       Date:  1984       Impact factor: 4.530
  5 in total

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