Literature DB >> 5536521

[Human pharmacokinetics of the new potent analgesic DL-trans-2-di-methylamino-1-phenyl-cyclohex-3-en-trans-1-carboxylic acid ethyl ester hydrochloride. 1. Blood level and excretion with urine and feces after single oral administration of 14C-labeled substance].

K O Vollmer, A Poisson.   

Abstract

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Year:  1970        PMID： 5536521

Source DB:  PubMed          Journal:  Arzneimittelforschung        ISSN： 0004-4172


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  3 in total

1.  A death case involving tilidine.

Authors:  M Van Boven; P Daenens; N Bruneel
Journal:  Arch Toxicol       Date:  1976-10-28       Impact factor: 5.153

2.  Contribution of CYP2C19 and CYP3A4 to the formation of the active nortilidine from the prodrug tilidine.

Authors:  Barbara Grün; Ulrike Merkel; Klaus-Dieter Riedel; Johanna Weiss; Gerd Mikus
Journal:  Br J Clin Pharmacol       Date:  2012-11       Impact factor: 4.335

3.  In vitro metabolism of the opioid tilidine and interaction of tilidine and nortilidine with CYP3A4, CYP2C19, and CYP2D6.

Authors:  Johanna Weiss; Evelyn Sawa; Klaus-Dieter Riedel; Walter Emil Haefeli; Gerd Mikus
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2008-05-31       Impact factor: 3.000
  3 in total

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