Literature DB >> 1036886

A death case involving tilidine.

M Van Boven, P Daenens, N Bruneel.   

Abstract

A fatal poisoning case due to the combination of a relative overdose of barbiturates (600 mg daily) and 750 mg of tilidine is reported. The concentrations of barbiturates and tilidine with its metabolites were determined in blood, liver, and urine.

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Year:  1976        PMID： 1036886     DOI： 10.1007/BF00351971

Source DB:  PubMed          Journal:  Arch Toxicol        ISSN： 0340-5761            Impact factor:   5.153


  8 in total

1.  [Metabolism of ethyl DL-trans-2-dimethylamino-1-phenylcyclohex-3-ene-trans-1-carboxylate hydrochloride. 1. Mass spectroscopic structural elucidation of metabolites I and II and their determination in various biological fluids].

Authors:  K O Vollmer; H Achenbach
Journal:  Arzneimittelforschung       Date:  1974-09

2.  [Valoron intoxication in attempted suicide].

Authors:  J Klapetek
Journal:  Munch Med Wochenschr       Date:  1973-01-26

3.  [Effect of intravenously administered Tilidine-HC1 on human respiration].

Authors:  L S Geisler; H D Rost
Journal:  Arzneimittelforschung       Date:  1972-02

4.  [Studies on cyclohexenes. I. Synthesis and reactions of 3-amino-4-phenyl-cyclohexenes-(1), a new class of analgesics].

Authors:  G Satzinger
Journal:  Justus Liebigs Ann Chem       Date:  1969

5.  [Human pharmacokinetics of the new potent analgesic DL-trans-2-di-methylamino-1-phenyl-cyclohex-3-en-trans-1-carboxylic acid ethyl ester hydrochloride. 1. Blood level and excretion with urine and feces after single oral administration of 14C-labeled substance].

Authors:  K O Vollmer; A Poisson
Journal:  Arzneimittelforschung       Date:  1970-08

6.  [Toxicological studies on a new potent analgesic].

Authors:  M Herrmann; J Wiegleb; F Leuschner
Journal:  Arzneimittelforschung       Date:  1970-08

7.  [Method for gas chromatographic determination of DL-trans-2-dimethyl-amino-1-phenyl-cyclohex-3-en-trans-1-carboxylic acid ethyl ester hydrochloride and its main metabolites in human plasma].

Authors:  K O Vollmer; F Zimmermann
Journal:  Arzneimittelforschung       Date:  1970-08

8.  [Pharmacology of a new potent analgesic].

Authors:  M Herrmann; W Steinbrecher; W Heldt
Journal:  Arzneimittelforschung       Date:  1970-08
  8 in total
  1 in total

1.  Poisoning and severe ventilatory depression after oral ingestion of the industrially produced analgesic mixture tilidine with naloxone (Valoron N solution)

Authors:  M Krüger; R Regenthal; M Richter; R Preiss
Journal:  Intensive Care Med       Date:  1998-07       Impact factor: 17.440
  1 in total

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