Literature DB >> 5511572

Histocompatibility type and immune responsiveness in random bred Hartley strain guinea pigs.

W J Martin, L Ellman, I Green, B Benacerraf.   

Abstract

Outbred Hartley strain guinea pigs capable of responding immunologically to 2,4-dinitrophenylated poly-L-lysine were shown to display a histocompatibility specificity in common with inbred strain 2 guinea pigs. This histocompatibility specificity was not detected in guinea pigs unable to respond immunologically to DNP-PLL. The result suggests that the poly-L-lysine specific immune response gene is very closely linked or even identical with a gene determining a major histocompatibility antigen in guinea pigs.

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Year:  1970        PMID: 5511572      PMCID: PMC2180499          DOI: 10.1084/jem.132.6.1259

Source DB:  PubMed          Journal:  J Exp Med        ISSN: 0022-1007            Impact factor:   14.307


  9 in total

1.  Leukemia in guinea-pigs.

Authors:  C C CONGDON; E LORENZ
Journal:  Am J Pathol       Date:  1954 Mar-Apr       Impact factor: 4.307

2.  Antigenicity of a new diethylnitrosamine-induced transplantable guinea pig hepatoma: pathology and formation of ascites variant.

Authors:  H J Rapp; W H Churchill; B S Kronman; R T Rolley; W G Hammond; T Borsos
Journal:  J Natl Cancer Inst       Date:  1968-07       Impact factor: 13.506

3.  Genetic control of the antibody response: relationship between immune response and histocompatibility (H-2) type.

Authors:  H O McDevitt; A Chinitz
Journal:  Science       Date:  1969-03-14       Impact factor: 47.728

4.  GENETIC CONTROL IN GUINEA PIGS OF IMMUNE RESPONSE TO CONJUGATES OF HAPTENS AND POLY-L-LYSINE.

Authors:  B B LEVINE; B BENACERRAF
Journal:  Science       Date:  1965-01-29       Impact factor: 47.728

5.  Linkage between the poly-L-lysine gene and the locus controlling the major histocompatibility antigens in strain 2 guinea pigs.

Authors:  L Ellman; I Green; W J Martin; B Benacerraf
Journal:  Proc Natl Acad Sci U S A       Date:  1970-06       Impact factor: 11.205

6.  A quantitative study of the stimulation of DNA synthesis in lymph node cell cultures by anti-lymphocyte serum, anti-gamma globulin serum, specific antigen, and phytohemagglutinin.

Authors:  J Foerster; J P Lamelin; I Green; B Benacerraf
Journal:  J Exp Med       Date:  1969-02-01       Impact factor: 14.307

7.  STUDIES ON ARTIFICIAL ANTIGENS. III. THE GENETIC CONTROL OF THE IMMUNE RESPONSE TO HAPTEN-POLY-L-LYSINE CONJUGATES IN GUINEA PIGS.

Authors:  B B LEVINE; A OJEDA; B BENACERRAF
Journal:  J Exp Med       Date:  1963-12-01       Impact factor: 14.307

8.  Studies on artifical antigens. I. Antigenicity of DNP-polylysine and DNP copolymer of lysine and glutamic acid in guinea pigs.

Authors:  F S KANTOR; A OJEDA; B BENCARERRAF
Journal:  J Exp Med       Date:  1963-01-01       Impact factor: 14.307

9.  Cellular localization of anti-DNP-PLL and anticonveyor albumin antibodies in genetic nonresponder guinea pigs immunized with DNP-PLL albumin complexes.

Authors:  I Green; P Vasalli; B Benacerraf
Journal:  J Exp Med       Date:  1967-03-01       Impact factor: 14.307

  9 in total
  10 in total

1.  Histocompatibility-linked immune response gene function in guinea pigs. Specific inhibition of antigen-induced lymphocyte proliferation by alloantisera.

Authors:  E M Shevach; W E Paul; I Green
Journal:  J Exp Med       Date:  1972-11-01       Impact factor: 14.307

2.  Analysis of HL-A antigens in patients with Hodgkin's disease and their families.

Authors:  J F Forbes; P J Morris
Journal:  J Clin Invest       Date:  1972-05       Impact factor: 14.808

3.  Function of macrophages in antigen recognition by guinea pig T lymphocytes. I. Requirement for histocompatible macrophages and lymphocytes.

Authors:  A S Rosenthal; E M Shevach
Journal:  J Exp Med       Date:  1973-11-01       Impact factor: 14.307

4.  Genetic control of bone marrow graft rejection. I. Determinant-specific difference of reactivity in two pairs of inbred mouse strains.

Authors:  G Cudkowicz
Journal:  J Exp Med       Date:  1971-07-01       Impact factor: 14.307

5.  Specific immune response genes of the guinea pig. 3. Linkage of the GA and GT immune response genes to histocompatibility genotypes in inbred guinea pigs.

Authors:  H G Bluestein; L Ellman; I Green; B Benacerraf
Journal:  J Exp Med       Date:  1971-12-01       Impact factor: 14.307

6.  Alloantiserum-induced inhibition of immune response gene product function. II. Genetic analysis of target antigens.

Authors:  E M Shevach; I Green; W E Paul
Journal:  J Exp Med       Date:  1974-03-01       Impact factor: 14.307

7.  Peculiar immunobiology of bone marrow allografts. I. Graft rejection by irradiated responder mice.

Authors:  G Cudkowicz; M Bennett
Journal:  J Exp Med       Date:  1971-07-01       Impact factor: 14.307

8.  Histocompatibility specificity.

Authors:  H G Bluestein; I Green; B Benacerraf
Journal:  J Exp Med       Date:  1971-12-01       Impact factor: 14.307

9.  Specific immune response genes of the guinea pig. V. Influence of the GA and GT immune response genes on the specificity of cellular and humoral immune responses to a terpolymer of L-glutamic acid, L-alanine, and L-tyrosine.

Authors:  H G Bluestein; I Green; P H Maurer; B Benacerraf
Journal:  J Exp Med       Date:  1972-01       Impact factor: 14.307

10.  Specific immune response genes of the guinea pig. II. Relationship between the poly-L-lysine gene and the genes controlling immune responsiveness to copolymers of L-glutamic acid and L-alanine and L-glutamic acid and L-tyrosine in random-bred Hartley guinea pigs.

Authors:  H G Bluestein; I Green; B Benacerraf
Journal:  J Exp Med       Date:  1971-08-01       Impact factor: 14.307

  10 in total

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