Literature DB >> 5505678

Fatty acid composition of phospholipids from platelets and erythrocytes in multiple sclerosis.

S Gul, A D Smith, R H Thompson, H P Wright, K J Zilkha.   

Abstract

The fatty acid composition of the phospholipids of red blood cells and blood platelets has been investigated in multiple sclerosis patients and in normal individuals. The variation in the platelet phospholipid fatty acid pattern in normals has been measured for the first time and has been shown to be small. The relative level of linoleate, expressed as a percentage of the five main fatty acids, was found to be significantly lower in the multiple sclerosis patients than in healthy individuals, both in the red cells and platelets. A highly significant correlation was found between serum linoleate and both platelet and red cell linoleate.

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Year:  1970        PMID： 5505678      PMCID： PMC493509          DOI： 10.1136/jnnp.33.4.506

Source DB:  PubMed          Journal:  J Neurol Neurosurg Psychiatry        ISSN： 0022-3050            Impact factor:   10.154


  20 in total

1.  Blood platelets in disseminated sclerosis; quantitative variations in peripheral blood.

Authors:  T FOG; I KRISTENSEN; H F HELWEG-LARSEN
Journal:  AMA Arch Neurol Psychiatry       Date:  1955-03

2.  Quantitative analysis of phospholipids by thin-layer chromatography and phosphorus analysis of spots.

Authors:  G Rouser; A N Siakotos; S Fleischer
Journal:  Lipids       Date:  1966-01       Impact factor: 1.880

3.  Comparison of phospholipid and fatty acid composition of human erythrocytes and platelets.

Authors:  P Cohen; A Derksen
Journal:  Br J Haematol       Date:  1969-10       Impact factor: 6.998

4.  Further studies on platelet adhesiveness and serum cholesteryl linoleate levels in multiple sclerosis.

Authors:  H Sanders; R H Thompson; H P Wright; K J Zilkha
Journal:  J Neurol Neurosurg Psychiatry       Date:  1968-08       Impact factor: 10.154

5.  Red blood cell size in multiple sclerosis.

Authors:  J Prineas
Journal:  Acta Neurol Scand       Date:  1968       Impact factor: 3.209

6.  Platelet adhesiveness in multiple sclerosis.

Authors:  H P Wright; R H Thompson; K J Zilkha
Journal:  Lancet       Date:  1965-11-27       Impact factor: 79.321

7.  Red blood cell fragility in multiple sclerosis.

Authors:  E A Caspary; F Sewell; E J Field
Journal:  Br Med J       Date:  1967-06-03

8.  Platelet stickiness in multiple sclerosis.

Authors:  J H Millar; J D Merrett; A M Dalby
Journal:  J Neurol Neurosurg Psychiatry       Date:  1966-06       Impact factor: 10.154

9.  Platelet stickiness in multiple sclerosis.

Authors:  P Millac
Journal:  Dtsch Z Nervenheilkd       Date:  1967

10.  Characterization and quantification of red cell lipids in normal man.

Authors:  P Ways; D J Hanahan
Journal:  J Lipid Res       Date:  1964-07       Impact factor: 5.922
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  25 in total

Review 1.  Specialized Pro-Resolving Lipid Mediators: Emerging Therapeutic Candidates for Multiple Sclerosis.

Authors:  Insha Zahoor; Shailendra Giri
Journal:  Clin Rev Allergy Immunol       Date:  2021-04       Impact factor: 8.667

2.  Lipid and fatty acid composition is altered in plaque tissue from multiple sclerosis brain compared with normal brain white matter.

Authors:  R Wilson; D R Tocher
Journal:  Lipids       Date:  1991-01       Impact factor: 1.880

3.  Double-blind trial of linoleate supplementation of the diet in multiple sclerosis.

Authors:  J H Millar; K J Zilkha; M J Langman; H P Wright; A D Smith; J Belin; R H Thompson
Journal:  Br Med J       Date:  1973-03-31

4.  Dietary intake of linoleic acid in multiple sclerosis and other diseases.

Authors:  N Callaghan; B Kearney; W C Love
Journal:  J Neurol Neurosurg Psychiatry       Date:  1973-08       Impact factor: 10.154

5.  Specific laboratory test for diagnosis of multiple sclerosis.

Authors:  E J Field; B K Shenton; G Joyce
Journal:  Br Med J       Date:  1974-03-09

6.  Linoleate and fatty-acid patterns of serum lipids in multiple sclerosis and other diseases.

Authors:  W C Love; A Cashell; M Reynolds; N Callaghan
Journal:  Br Med J       Date:  1974-07-06

7.  Red blood cell glutathione peroxidase activity in multiple sclerosis.

Authors:  B Zachara; J Gromadzińska; J Czernicki; Z Maciejek; H Chmielewski
Journal:  Klin Wochenschr       Date:  1984-02-15

8.  Evaluation of the erythrocyte-UFA (E-UFA) mobility test for the diagnosis of multiple sclerosis.

Authors:  J Cuypers; H Reddemann
Journal:  J Neurol Neurosurg Psychiatry       Date:  1980-11       Impact factor: 10.154

9.  Lipid peroxidation products and antioxidant proteins in plasma and cerebrospinal fluid from multiple sclerosis patients.

Authors:  M I Hunter; B C Nlemadim; D L Davidson
Journal:  Neurochem Res       Date:  1985-12       Impact factor: 3.996

10.  Linoleate metabolism in multiple sclerosis.

Authors:  J Belin; N Pettet; A D Smith; R H Thompson; K J Zilkha
Journal:  J Neurol Neurosurg Psychiatry       Date:  1971-02       Impact factor: 10.154
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