Literature DB >> 5475023

Synthesis of amino acids by the heating of formaldehyde and ammonia.

S W Fox, C R Windsor.   

Abstract

The heating of formaldehyde and ammonia yields a product that, on hydrolysis, is converted into seven amino acids: aspartic acid, glutamic acid, serine, proline, valine, glycine, and alanine. Glycine is the predominant amino acid. Inasmuch as formaldehyde and ammonia have been identified as compounds in galactic clouds, these experimental results are interpreted in a cosmochemical and geochemical context.

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Year:  1970        PMID: 5475023     DOI: 10.1126/science.170.3961.984

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  20 in total

1.  A system of two polymerases--a model for the origin of life.

Authors:  V Kunin
Journal:  Orig Life Evol Biosph       Date:  2000-10       Impact factor: 1.950

2.  The role of submarine hydrothermal systems in the synthesis of amino acids.

Authors:  A D Aubrey; H J Cleaves; Jeffrey L Bada
Journal:  Orig Life Evol Biosph       Date:  2008-11-26       Impact factor: 1.950

Review 3.  Which amino acids should be used in prebiotic chemistry studies?

Authors:  Dimas A M Zaia; Cássia Thaïs B V Zaia; Henrique De Santana
Journal:  Orig Life Evol Biosph       Date:  2008-10-17       Impact factor: 1.950

Review 4.  The energetics of organic synthesis inside and outside the cell.

Authors:  Jan P Amend; Douglas E LaRowe; Thomas M McCollom; Everett L Shock
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2013-06-10       Impact factor: 6.237

5.  Response to comments on thermal polypeptides by P. A. Temussi et al.

Authors:  S W Fox
Journal:  J Mol Evol       Date:  1976-10-27       Impact factor: 2.395

6.  Reaction behaviors of glycine under super- and subcritical water conditions.

Authors:  Dimitar K Alargov; Shigeru Deguchi; Kaoru Tsujii; Koki Horikoshi
Journal:  Orig Life Evol Biosph       Date:  2002-02       Impact factor: 1.950

Review 7.  Origins of biological information and the genetic code.

Authors:  S W Fox
Journal:  Mol Cell Biochem       Date:  1974-04-15       Impact factor: 3.396

8.  Quantum chemical study of the thermodynamics, kinetics of formation and bonding of H2CN: relevance to prebiotic chemistry.

Authors:  G H Loew; S Chang
Journal:  J Mol Evol       Date:  1974       Impact factor: 2.395

9.  Amino acid precursors in lunar samples.

Authors:  S W Fox; K Harada; P E Hare
Journal:  Space Life Sci       Date:  1972-10

10.  Prebiotic synthesis of hydrophobic and protein amino acids.

Authors:  D Ring; Y Wolman; N Friedmann; S L Miller
Journal:  Proc Natl Acad Sci U S A       Date:  1972-03       Impact factor: 11.205

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