Literature DB >> 54742

Healing of gastric ulcer during treatment with cimetidine.

R E Pounder, R H Hunt, M Stekelman, G J Milton-Thompson, J J Misiewicz.   

Abstract

10 patients with benign gastric ulcer were treated with cimetidine 0-8 to 1-6 g/day for six weeks. Relief of symptoms was rapid. Endoscopy at the end of treatment showed that all the ulcers had healed. Healing was not associated with an improvement of acute atrophic gastritis nor with any change of gastric mucosal potential difference. No untoward clinical or laboratory effects were observed.

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Year:  1976        PMID: 54742     DOI: 10.1016/s0140-6736(76)90088-x

Source DB:  PubMed          Journal:  Lancet        ISSN: 0140-6736            Impact factor:   79.321


  16 in total

1.  Rational basis for the application of cimetidine in the therapy of human gastric hypersecretion.

Authors:  B Simon; H Kather
Journal:  Br J Clin Pharmacol       Date:  1977-08       Impact factor: 4.335

2.  Gastric ulcer: effect of healing on gastric acid secretion and fasting serum gastrin levels.

Authors:  J M Boyle; A L Hurwitz; R S Jones; C M Mansbach
Journal:  Am J Dig Dis       Date:  1977-12

Review 3.  Gastroenterology in the armed forces.

Authors:  G Milton-Thompson
Journal:  Gut       Date:  1989-11       Impact factor: 23.059

4.  Duodenal ulcers that will not heal.

Authors:  R E Pounder
Journal:  Gut       Date:  1984-07       Impact factor: 23.059

5.  The preventive effect of cimetidine on producing stress ulcer in rats.

Authors:  K Sugimachi; S Sufian; T Matsumoto; T Nakamura; K Inokuchi
Journal:  Jpn J Surg       Date:  1978-09

6.  The direct excitatory effects of cimetidine on the smooth muscle of guinea pig ileum.

Authors:  S Vyas; S C Verma
Journal:  Agents Actions       Date:  1981-05

7.  Effects of cimetidine on the healing and recurrence of duodenal ulcers and gastric ulcers.

Authors:  M Tatsuta; H Iishi; S Okuda
Journal:  Gut       Date:  1986-10       Impact factor: 23.059

8.  Effects of cimetidine on healing of chronic gastric and duodenal ulcers in dogs.

Authors:  S Okabe; K Takeuchi; T Murata; T Urushidani
Journal:  Am J Dig Dis       Date:  1978-02

9.  Controlled comparison of cimetidine and carbenoxolone sodium in gastric ulcer.

Authors:  S J La Brooy; R H Taylor; R H Hunt; P L Golding; J M Laidlaw; R G Chapman; R E Pounder; S H Vincent; D G Colin-Jones; G J Milton-Thompson; J J Misiewicz
Journal:  Br Med J       Date:  1979-05-19

Review 10.  Cimetidine: a review of its pharmacological properties and therapeutic efficacy in peptic ulcer disease.

Authors:  R N Brogden; R C Heel; T M Speight; G S Avery
Journal:  Drugs       Date:  1978-02       Impact factor: 9.546

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