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Literature DB >> 546939

Identification and quantitation of nucleosides, bases and other UV-absorbing compounds in serum, using reversed-phase high-performance liquid chromatography. II. Evaluation of human sera.

R A Hartwick, A M Krstulovic, P R Brown.

Abstract

The reversed-phase mode of high-performance liquid chromatography was used to investigate the profiles of low-molecular-weight, UV-absorbing compounds in human serum. Identification techniques are described which allow for the identification of picomole amounts of the nucleosides, bases and other compounds in several microliters of serum ultrafiltrate. The sera from 31 normal subjects (17 males, 14 females) showed very consistent profiles. A total of 12 compounds were identified and quantified in normal serum. The analysis of sera from over 150 patients with various types of neoplasia and other diseases showed serum profiles significantly different from normal profile.

Entities: Chemical Disease Species

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Year: 1979 PMID： 546939 DOI： 10.1016/s0021-9673(00)95286-5

Source DB: PubMed Journal: J Chromatogr

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Cited

17 in total

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Journal: Antimicrob Agents Chemother Date: 1997-08 Impact factor: 5.191

2. GMP synthase is essential for viability and infectivity of Trypanosoma brucei despite a redundant purine salvage pathway.

Authors: Qiong Li; Christopher Leija; Filipa Rijo-Ferreira; Jun Chen; Igor Cestari; Kenneth Stuart; Benjamin P Tu; Margaret A Phillips
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3. Identification of suppressive components in "Haemophilus somnus" fractions which inhibit bovine polymorphonuclear leukocyte function.

Authors: Y W Chiang; M L Kaeberle; J A Roth
Journal: Infect Immun Date: 1986-06 Impact factor: 3.441

4. Hypoxanthine increases basal and FGF-stimulated growth of porcine aortic endothelial cells in media with calf or newborn bovine serum.

Authors: Y Hayashi; S Hirai; A Ichikawa
Journal: In Vitro Cell Dev Biol Date: 1990-09

5. Proceedings of a symposium on crystal-related arthropathies. 22 October and 23 October, 1982, Bristol Polytechnic, Bristol.

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Journal: Ann Rheum Dis Date: 1983-08 Impact factor: 19.103

10. Helicobacter pylori salvages purines from extracellular host cell DNA utilizing the outer membrane-associated nuclease NucT.

Authors: George W Liechti; Joanna B Goldberg
Journal: J Bacteriol Date: 2013-07-26 Impact factor: 3.490

Identification and quantitation of nucleosides, bases and other UV-absorbing compounds in serum, using reversed-phase high-performance liquid chromatography. II. Evaluation of human sera.

1. Hypoxanthine phosphoribosyltransferase from Trypanosoma cruzi as a target for structure-based inhibitor design: crystallization and inhibition studies with purine analogs.

2. GMP synthase is essential for viability and infectivity of Trypanosoma brucei despite a redundant purine salvage pathway.

3. Identification of suppressive components in "Haemophilus somnus" fractions which inhibit bovine polymorphonuclear leukocyte function.

4. Hypoxanthine increases basal and FGF-stimulated growth of porcine aortic endothelial cells in media with calf or newborn bovine serum.

5. Proceedings of a symposium on crystal-related arthropathies. 22 October and 23 October, 1982, Bristol Polytechnic, Bristol.

6. GuaA and GuaB are essential for Borrelia burgdorferi survival in the tick-mouse infection cycle.

7. Helicobacter pylori relies primarily on the purine salvage pathway for purine nucleotide biosynthesis.

Review 8. Physiological concentrations of purines and pyrimidines.

9. Ribonucleosides as minor milk constituents.

10. Helicobacter pylori salvages purines from extracellular host cell DNA utilizing the outer membrane-associated nuclease NucT.