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Literature DB >> 5466900

Gallium-67 localization in rat and mouse tumors.

R L Hayes, B Nelson, D C Swartzendruber, J E Carlton, B L Byrd.

Abstract

Various nonosseous tumors in mice and rats concentrate gallium-67-ESR-586 preputial gland carcinoma, P-1798 lymphosarcoma, C3H/ HeJ mammary tumor, AKR/J thymic lymphoma, R-3259 giant cell sarcoma, Walker-256 carcinosarcoma, and a new transplantable neoplasm of rats. This last tumor showed the greatest affinity for galliun. Viable tumor cells are mainly responsible for uptake of gallium-67; autoradiographic studies indicate it is chiefly located in tumor cytoplasm.

Entities: Chemical Disease Species

Mesh：

Substances：
Gallium

Year: 1970 PMID： 5466900 DOI： 10.1126/science.167.3916.289

Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728

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Cited

14 in total

1. The relationship between Ga-67 accumulation and cell cycle in malignant tumor cells in vitro.

Authors: T Higashi; H Wakao; M Yamaguchi; K Suga
Journal: Eur J Nucl Med Date: 1988

2. The relationship between 67Ga accumulation and ATP metabolism in tumor cells in vitro.

Authors: T Higashi; M Kobayashi; H Wakao; Y Jinbu
Journal: Eur J Nucl Med Date: 1989

3. Lymphomatous involvement of the stomach demonstrated by gallium-67 scanning.

Authors: L Que; W McCartney; A Hankins; P Hoffer
Journal: Am J Dig Dis Date: 1974-03

4. Phase II trial of gallium nitrate, amonafide and teniposide in metastatic non-small cell lung cancer. An Eastern Cooperative Oncology Group study (E2588).

Authors: A Y Chang; Z N Tu; J L Smith; P Bonomi; T J Smith; P H Wiernik; R Blum
Journal: Invest New Drugs Date: 1995 Impact factor: 3.850

5. The urinary excretion of gallium-67 citrate in patients with neoplastic disease.

Authors: M A Zivanovic; V R McCready; D M Taylor
Journal: Eur J Nucl Med Date: 1979-08-01

Review 6. Gallium nitrate. A review of its pharmacological properties and therapeutic potential in cancer related hypercalcaemia.

Authors: P A Todd; A Fitton
Journal: Drugs Date: 1991-08 Impact factor: 9.546

Gallium-67 localization in rat and mouse tumors.

1. The relationship between Ga-67 accumulation and cell cycle in malignant tumor cells in vitro.

2. The relationship between 67Ga accumulation and ATP metabolism in tumor cells in vitro.

3. Lymphomatous involvement of the stomach demonstrated by gallium-67 scanning.

4. Phase II trial of gallium nitrate, amonafide and teniposide in metastatic non-small cell lung cancer. An Eastern Cooperative Oncology Group study (E2588).

5. The urinary excretion of gallium-67 citrate in patients with neoplastic disease.

Review 6. Gallium nitrate. A review of its pharmacological properties and therapeutic potential in cancer related hypercalcaemia.

Review 7. Gallium-67 scintigraphy: a cornerstone in functional imaging of lymphoma.

8. Uptake of 67Ga-6-mercaptopurines in Morris hepatoma-3924 A.

9. Tumor and liver uptake models of 67Ga-citrate.

10. Antitumor activity and toxicity of salts of inorganic group 3a metals: aluminum, gallium, indium, and thallium.