Literature DB >> 54586

Does phenylethylamine cause schizophrenia?

M Sandler, G P Reynolds.   

Abstract

The model psychosis associated with amphetamine overdosage is known to bear a close resemblance to acute paranoid schizophrenia. Amphetamine is chemically similar to the endogenous sympathomimetic amine, phenylethylamine, which possess many of its pharmacological properties. It is suggested that some cases of schizophrenia may be associated with an abnormal phenylethylamine response, either from increased concentrations of the amine or from abnormal receptor sensitivity to it.

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Year:  1976        PMID: 54586     DOI: 10.1016/s0140-6736(76)90156-2

Source DB:  PubMed          Journal:  Lancet        ISSN: 0140-6736            Impact factor:   79.321


  14 in total

Review 1.  The emerging role of trace amine-associated receptor 1 in the functional regulation of monoamine transporters and dopaminergic activity.

Authors:  Gregory M Miller
Journal:  J Neurochem       Date:  2011-01       Impact factor: 5.372

2.  Phenylethylamine formation in perfused rat liver [proceedings].

Authors:  K Blau; B Goodwin; H F Woods; M B Youdim
Journal:  Br J Pharmacol       Date:  1976-11       Impact factor: 8.739

3.  Environmental experience produces qualitative changes in the stimulant effects of beta-phenylethylamine in rats.

Authors:  C T Dourish; S J Cooper
Journal:  Psychopharmacology (Berl)       Date:  1984       Impact factor: 4.530

4.  Deprenyl administration in man: a selective monoamine oxidase B inhibitor without the 'cheese effect'.

Authors:  J D Elsworth; V Glover; G P Reynolds; M Sandler; A J Lees; P Phuapradit; K M Shaw; G M Stern; P Kumar
Journal:  Psychopharmacology (Berl)       Date:  1978-04-14       Impact factor: 4.530

5.  Trace amines: identification of a family of mammalian G protein-coupled receptors.

Authors:  B Borowsky; N Adham; K A Jones; R Raddatz; R Artymyshyn; K L Ogozalek; M M Durkin; P P Lakhlani; J A Bonini; S Pathirana; N Boyle; X Pu; E Kouranova; H Lichtblau; F Y Ochoa; T A Branchek; C Gerald
Journal:  Proc Natl Acad Sci U S A       Date:  2001-07-17       Impact factor: 11.205

6.  Tolerance development to a disruptive effect of beta-phenylethylamine (PEA) on a learned behavior in rats.

Authors:  D M Stoff; E A Moja; D R Jeffery; J C Gillin; R J Wyatt
Journal:  Psychopharmacology (Berl)       Date:  1979-11       Impact factor: 4.530

7.  Urinary phenylethylamine correlates positively with hypomania, and negatively with depression, paranoia, and social introversion on the MMPI.

Authors:  H W Moises; P Waldmeier; H Beckmann
Journal:  Eur Arch Psychiatry Neurol Sci       Date:  1986

8.  A pharmacological analysis of the hyperactivity syndrome induced by beta-phenylethylamine in the mouse.

Authors:  C T Dourish
Journal:  Br J Pharmacol       Date:  1982-09       Impact factor: 8.739

Review 9.  Trace amine-associated receptor 1-Family archetype or iconoclast?

Authors:  David K Grandy
Journal:  Pharmacol Ther       Date:  2007-07-17       Impact factor: 12.310

10.  Pharmacogenetics of phenylethylamine: determination of heritability and genetic transmission of locomotor effects in recombinant inbred strains of mice.

Authors:  D V Jeste; D M Stoff; R Rawlings; R J Wyatt
Journal:  Psychopharmacology (Berl)       Date:  1984       Impact factor: 4.530

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