| Literature DB >> 54586 |
Abstract
The model psychosis associated with amphetamine overdosage is known to bear a close resemblance to acute paranoid schizophrenia. Amphetamine is chemically similar to the endogenous sympathomimetic amine, phenylethylamine, which possess many of its pharmacological properties. It is suggested that some cases of schizophrenia may be associated with an abnormal phenylethylamine response, either from increased concentrations of the amine or from abnormal receptor sensitivity to it.Entities:
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Year: 1976 PMID: 54586 DOI: 10.1016/s0140-6736(76)90156-2
Source DB: PubMed Journal: Lancet ISSN: 0140-6736 Impact factor: 79.321