Literature DB >> 54518

Apparatus for patient-controlled administration of intravenous narcotics during labour.

J M Evans, M Rosen, J MacCarthy, M I Hogg.   

Abstract

The intermittent intravenous administration of narcotic analgesics had advantages over intramuscular administration, but is often impracticable. The design of a prototype apparatus is described, from which analgesic, pethidine, can be self-administered intravenously during labour. The apparatus consists of a syringe pump and control system from which the patient can demand an increment of analgesic. The minimum interval between increments and the dose of the increment are preset. A demand for analgesia is only successful when the patient passes a reaction-time test, subsequently modified. The apparatus has been used by forty-two mothers in labour. The mean total dose self-administered (2.2 mg/kg) was well within the prescribed limits, suggesting that mothers regulated their demand. The apparatus appears acceptable and safe in labour. The apparatus will probably be of value in comparative studies of analgesics.

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Year:  1976        PMID: 54518     DOI: 10.1016/s0140-6736(76)92910-x

Source DB:  PubMed          Journal:  Lancet        ISSN: 0140-6736            Impact factor:   79.321


  21 in total

Review 1.  Pharmacokinetic optimisation of opioid treatment in acute pain therapy.

Authors:  R N Upton; T J Semple; P E Macintyre
Journal:  Clin Pharmacokinet       Date:  1997-09       Impact factor: 6.447

Review 2.  Treatment of pain in acute myocardial infarction.

Authors:  J Herlitz; A Hjalmarson; F Waagstein
Journal:  Br Heart J       Date:  1989-01

3.  Abstracts: annual meeting of the Canadian Anesthetists' Society. June 26-29, 1988, Halifax, Nova Scotia.

Authors: 
Journal:  Can J Anaesth       Date:  1988-05       Impact factor: 5.063

4.  Comparison of buprenorphine and pethidine given intravenously on demand to relieve postoperative pain.

Authors:  K Chakravarty; W Tucker; M Rosen; M D Vickers
Journal:  Br Med J       Date:  1979-10-13

5.  Patient controlled analgesia following myocardial infarction.

Authors:  R J Eltringham; M B Jones; A N Burlingham; G B Smith
Journal:  Intensive Care Med       Date:  1983       Impact factor: 17.440

Review 6.  Postoperative pain control.

Authors:  Veerabhadram Garimella; Christina Cellini
Journal:  Clin Colon Rectal Surg       Date:  2013-09

7.  Patient-controlled analgesic therapy, Part II: Individual analgesic demand and analgesic plasma concentrations of pethidine in postoperative pain.

Authors:  A Tamsen; P Hartvig; C Fagerlund; B Dahlström
Journal:  Clin Pharmacokinet       Date:  1982 Mar-Apr       Impact factor: 6.447

8.  Meperidine infusion for postoperative analgesia in grossly obese patients.

Authors:  J S Sprigge; D S East; G S Fox; R I Ogilvie; P E Otton; D R Bevan
Journal:  Can Anaesth Soc J       Date:  1982-03

9.  An open comparison between routine and self-administered postoperative pain relief.

Authors:  P J Slattery; M Harmer; M Rosen; M D Vickers
Journal:  Ann R Coll Surg Engl       Date:  1983-01       Impact factor: 1.891

Review 10.  Newer methods of delivery of opiates for relief of pain.

Authors:  P J Slattery; R A Boas
Journal:  Drugs       Date:  1985-12       Impact factor: 9.546

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