Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Sodium inactivation. Experimental test of two models.

Literature DB >> 5449914

Sodium inactivation. Experimental test of two models.

Abstract

Analyses of inactivation experiments performed on unperfused axons of the squid have been compared with the predictions of the Hodgkin-Huxley and the Hoyt mathematical models for the early (sodium) conductance. The results are in good agreement with the latter and in disagreement with the former.

Entities: Chemical Disease

Mesh：

Substances：
Sodium

Year: 1970 PMID： 5449914 PMCID： PMC1367785 DOI： 10.1016/S0006-3495(70)86323-8

Source DB: PubMed Journal: Biophys J ISSN： 0006-3495 Impact factor: 4.033

8 in total

1. THE SQUID GIANT AXON. MATHEMATICAL MODELS.

Authors: R C HOYT
Journal: Biophys J Date: 1963-09 Impact factor: 4.033

2. INTERNALLY PERFUSED SQUID AXONS STUDIED UNDER VOLTAGE CLAMP CONDITIONS. II. RESULTS. THE EFFECTS OF INTERNAL POTASSIUM AND SODIUM ON MEMBRANE ELECTRICAL CHARACTERISTICS.

Authors: W J ADELMAN; Y B FOK
Journal: J Cell Comp Physiol Date: 1964-12

3. A quantitative description of membrane current and its application to conduction and excitation in nerve.

Authors: A L HODGKIN; A F HUXLEY
Journal: J Physiol Date: 1952-08 Impact factor: 5.182

4. Dynamic asymmetries in the squid axon membrane.

Authors: W J Adelman; J P Senft
Journal: J Gen Physiol Date: 1968-05 Impact factor: 4.086

5. Voltage clamp experiments on internally perfused giant axons.

Authors: W K Chandler; H Meves
Journal: J Physiol Date: 1965-10 Impact factor: 5.182

6. Sodium inactivation in nerve fibers.

Authors: R C Hoyt
Journal: Biophys J Date: 1968-10 Impact factor: 4.033

7. An analysis of pore size in excitable membranes.

Authors: L J MULLINS
Journal: J Gen Physiol Date: 1960-05 Impact factor: 4.086

8. The influence of external potassium on the inactivation of sodium currents in the giant axon of the squid, Loligo pealei.

Authors: W J Adelman; Y Palti
Journal: J Gen Physiol Date: 1969-06 Impact factor: 4.086

8 in total

22 in total

1. A transient excited state model for sodium permeability changes in excitable membranes.

Authors: E Jakobsson; C Scudiero
Journal: Biophys J Date: 1975-06 Impact factor: 4.033

2. Quantitative description of the sodium conductance of the giant axon of Myxicola in terms of a generalized second-order variable.

Authors: L Goldman
Journal: Biophys J Date: 1975-02 Impact factor: 4.033

3. Determination of the resistance in series with the membranes of giant axons.

Authors: L Binstock; W J Adelman; P Senft; H Lecar
Journal: J Membr Biol Date: 1975-04-23 Impact factor: 1.843

4. Inactivation of sodium channels: second order kinetics in myelinated nerve.

Authors: S Y Chiu
Journal: J Physiol Date: 1977-12 Impact factor: 5.182

5. On the theory of ion transport across the nerve membrane. VI. Free energy and activation free energies of conformational change.

Authors: T L Hill; Y Chen
Journal: Proc Natl Acad Sci U S A Date: 1972-07 Impact factor: 11.205

6. Determinants of time-dependent membrane conductance. The nonrole of classical ion-membrane molecule interactions.

Authors: M C Mackey; M L McNeel
Journal: Biophys J Date: 1973-08 Impact factor: 4.033

7. A systems theoretical approach to biological membranes. I. Formulation of a generalized model for electrical phenomena in excitable membranes.

Authors: B Michaelis; R A Chaplain
Journal: Kybernetik Date: 1973-03

8. Activation-inactivation coupling in Myxicola giant axons injected with tetraethylammonium.

Authors: C L Schauf; T L Pencek; F A Davis
Journal: Biophys J Date: 1976-09 Impact factor: 4.033

9. Effect of calcium upon sodium inactivation in the giant axon of Loligo pealei.

Authors: J J Shoukimas
Journal: J Membr Biol Date: 1978-01-18 Impact factor: 1.843

10. Kinetic properties of electrostatic pores with orientable dipoles, for Na+ and K+ transport through biological membranes.

Authors: D Van Lamsweerde-Gallez; A Meessen
Journal: J Membr Biol Date: 1978-04-20 Impact factor: 1.843