Literature DB >> 5441684

Ochratoxin A: inhibition of mitochondrial respiration.

J H Moore, B Truelove.   

Abstract

Ochratoxin A is a fungal metabolite which induces pathological changes in animals. The toxin was isolated from cultures of Aspergillus ochraceus and purified by thin-layer chromatography. Ochratoxin A and one of its hydrolysis products, dihydroisocoumarin, severely inhibited coupled respiration when applied at low concentration to rat liver mitochondria.

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Year:  1970        PMID： 5441684     DOI： 10.1126/science.168.3935.1102

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  7 in total

1.  Transformation of the mycotoxin ochratoxin A in plants. 2. Time course and rates of degradation and metabolite production in cell-suspension cultures of different crop plants.

Authors:  M Ruhland; G Engelhardt; P R Wallnöfer
Journal:  Mycopathologia       Date:  1996       Impact factor: 2.574

2.  Apoptosis in cultured renal epithelial cells caused by ochratoxin A.

Authors:  G Schwerdt; R Freudinger; C Schuster; S Silbernagl; M Gekle
Journal:  Mycotoxin Res       Date:  2000-06       Impact factor: 3.833

3.  Neurochemical effects of prenatal treatment with ochratoxin A on fetal and adult mouse brain.

Authors:  M Tamaru; Y Hirata; T Matsutani
Journal:  Neurochem Res       Date:  1988-12       Impact factor: 3.996

Review 4.  Biological activities of mycotoxins.

Authors:  A W Hayes
Journal:  Mycopathologia       Date:  1978-12-18       Impact factor: 2.574

Review 5.  Glycogen storage diseases in animals and their potential value as models of human disease.

Authors:  H C Walvoort
Journal:  J Inherit Metab Dis       Date:  1983       Impact factor: 4.982

6.  Acute toxicity of ochratoxins A and B in chicks.

Authors:  J C Peckham; B Doupnik; O H Jones
Journal:  Appl Microbiol       Date:  1971-03

7.  Tropical cirrhosis and hepatoma.

Authors:  A Coady
Journal:  J R Coll Physicians Lond       Date:  1976-01
  7 in total

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