Literature DB >> 5440587

Haematemesis and melaena, with special reference to factors influencing the outcome.

K F Schiller, S C Truelove, D G Williams.   

Abstract

In a study of 2,149 emergency admissions because of haematemesis or melaena during a 15-year period, the sex ratio, age distribution, and main diagnostic groups showed no major change. Various factors affected the prognosis, such as the age of the patient, the underlying diagnosis, a low blood pressure on arrival at hospital, gross anaemia on arrival there, and the pattern of bleeding after admission. The fatality rate remained virtually constant throughout the period studied in spite of changes in diagnostic methods and management. There was a changing pattern in the type of operation performed in the treatment of bleeding peptic ulcer. Vagotomy combined with a drainage procedure and with a direct surgical attack on the bleeding point became more widely used at the expense of Polya or Billroth I partial gastrectomy and gave the best results. It is at first paradoxical that improved surgical results should not be reflected in a general improvement in the fatality rate, but this finding can be explained by the smaller proportion of patients treated by emergency surgery in the later years of the period studied. It is concluded that emergency surgery should be performed more frequently and that vagotomy plus drainage is the operation of choice in the peptic ulcer group.

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Year:  1970        PMID: 5440587      PMCID: PMC1699731          DOI: 10.1136/bmj.2.5700.7

Source DB:  PubMed          Journal:  Br Med J        ISSN: 0007-1447


  66 in total

1.  Specialized gastrointestinal units for the management of upper gastrointestinal haemorrhage.

Authors:  J D Sanderson; R F Taylor; S Pugh; F R Vicary
Journal:  Postgrad Med J       Date:  1990-08       Impact factor: 2.401

Review 2.  Upper gastrointestinal bleeding--when to operate.

Authors:  K E Wheatley; P W Dykes
Journal:  Postgrad Med J       Date:  1990-11       Impact factor: 2.401

Review 3.  Gastroenterology services in the UK. The burden of disease, and the organisation and delivery of services for gastrointestinal and liver disorders: a review of the evidence.

Authors:  J G Williams; S E Roberts; M F Ali; W Y Cheung; D R Cohen; G Demery; A Edwards; M Greer; M D Hellier; H A Hutchings; B Ip; M F Longo; I T Russell; H A Snooks; J C Williams
Journal:  Gut       Date:  2007-02       Impact factor: 23.059

Review 4.  Bleeding peptic ulcer--endoscopic and pharmacological management.

Authors:  S C Jones; A T Axon
Journal:  Postgrad Med J       Date:  1991-07       Impact factor: 2.401

5.  The management of upper gastrointestinal haemorrhage in a tropical country.

Authors:  T H Rao; G K Pande; P Sahni; S Nundy
Journal:  Arch Emerg Med       Date:  1991-09

6.  Epinephrine injection therapy versus a combination of epinephrine injection and endoscopic hemoclip in the treatment of bleeding ulcers.

Authors:  Tju-Siang Chua; Kwong-Ming Fock; Tay-Meng Ng; Eng-Kiong Teo; Jessica-Yi-Lyn Tan; Tiing-Leong Ang
Journal:  World J Gastroenterol       Date:  2005-02-21       Impact factor: 5.742

7.  The metabolic effects of moderately severe upper gastrointestinal haemorrhage in man.

Authors:  K J Foster; K G Alberti; C Binder; G Holdstock; S J Karran; C L Smith; S Talbot; D C Turnell
Journal:  Postgrad Med J       Date:  1982-01       Impact factor: 2.401

8.  Comparison between cimetidine and Caved-S in the treatment of gastric ulceration, and subsequent maintenance therapy.

Authors:  A G Morgan; W A McAdam; C Pacsoo; A Darnborough
Journal:  Gut       Date:  1982-06       Impact factor: 23.059

9.  Risk factors for mortality in severe upper gastrointestinal bleeding.

Authors:  Frank Klebl; Nicole Bregenzer; Lars Schöfer; Wolfgang Tamme; Julia Langgartner; Jürgen Schölmerich; Helmut Messmann
Journal:  Int J Colorectal Dis       Date:  2004-08-19       Impact factor: 2.571

Review 10.  Why have controlled trials failed to demonstrate a benefit of esophagogastroduodenoscopy in acute upper gastrointestinal bleeding? A probability model analysis.

Authors:  R A Erickson; M E Glick
Journal:  Dig Dis Sci       Date:  1986-07       Impact factor: 3.199

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