Literature DB >> 543700

N-demethylation of nicotine and reduction of nicotine-1'-N-oxide by Microsporum gypseum.

R D Sindelar, J P Rosazza, C F Barfknecht.   

Abstract

Several microorganisms were examined for their abilities to convert S-nicotine into nornicotine. Five microorganisms including Microsporum gypseum (ATCC 11395) produced nornicotine and three unknown metabolites. M. gypseum efficiently reduced nicotine-1'-N-oxide to nicotine, but no nornicotine was obtained when the N-oxide was used as substrate.

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Year:  1979        PMID： 543700      PMCID： PMC243596          DOI： 10.1128/aem.38.5.836-839.1979

Source DB:  PubMed          Journal:  Appl Environ Microbiol        ISSN： 0099-2240            Impact factor:   4.792


  16 in total

1.  MASS SPECTROMETRY IN STRUCTURAL AND STEREOCHEMICAL PROBLEMS. LXXII. A STUDY OF THE FRAGMENTATION PROCESSES OF SOME TOBACCO ALKALOIDS.

Authors:  A M DUFFIELD; H BUDZIKIEWICZ; C DJERASSI
Journal:  J Am Chem Soc       Date:  1965-07-05       Impact factor: 15.419

2.  Phytochemical studies on the tobacco alkaloids. I. Optical rotatory power of nornicotine.

Authors:  T KISAKI; E TAMAKI
Journal:  Arch Biochem Biophys       Date:  1961-02       Impact factor: 4.013

3.  Bioreduction of pyridine N-oxide.

Authors:  A MAY
Journal:  Enzymologia       Date:  1957-01-30

4.  Enzymic oxidation of (-)-nicotine by guinea-pig tissues in vitro.

Authors:  J Booth; E Boyland
Journal:  Biochem Pharmacol       Date:  1971-02       Impact factor: 5.858

5.  The separation of ten tobacco alkaloids by thin-layer chromatography.

Authors:  O Fejér-Kossey
Journal:  J Chromatogr       Date:  1967-12

6.  Intracellular localization and properties of trimethylamine-N-oxide reductase in Vibrio parahaemolyticus.

Authors:  T Unemoto; M Hayashi; K Miyaki; M Hayashi
Journal:  Biochim Biophys Acta       Date:  1965-11-22

7.  Microbial transformations of antitumor compounds. 1. Conversion of acronycine to 9-hydroxyacronycine by Cunninghamella echinulata.

Authors:  R E Betts; D E Walters; J P Rosazza
Journal:  J Med Chem       Date:  1974-06       Impact factor: 7.446

8.  Microbial transformation of antibiotics. 3. Conversion of clindamycin to 1'-demethylclindamycin and clindamycin sulfoxide by Streptomyces species.

Authors:  A D Argoudelis; J H Coats; D J Mason; O K Sebek
Journal:  J Antibiot (Tokyo)       Date:  1969-07       Impact factor: 2.649

9.  Microbiological transformation of 6,14-endo-ethenotetrahydrothebaine alkaloids.

Authors:  L A Mitscher; W W Andres; G O Morton; E L Patterson
Journal:  Experientia       Date:  1968-02-15

Review 10.  The oxidative cleavage of alkyl-nitrogen bonds in micro-organisms.

Authors:  P J Large
Journal:  Xenobiotica       Date:  1971 Jul-Oct       Impact factor: 1.908
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  4 in total

1.  Possible Role of Formaldehyde in the Apoptotic and Mitotic Effect of 1-Methyl-Ascorbigen.

Authors:  Béla Szende; Ernô Tyihák; Gyula Szókán; György Kátay
Journal:  Pathol Oncol Res       Date:  1995       Impact factor: 3.201

2.  Characterization of a Novel Nicotine Degradation Gene Cluster ndp in Sphingomonas melonis TY and Its Evolutionary Analysis.

Authors:  Haixia Wang; Xiao-Yang Zhi; Jiguo Qiu; Longxiang Shi; Zhenmei Lu
Journal:  Front Microbiol       Date:  2017-03-09       Impact factor: 5.640

3.  Endophytic Fungal Community of Tobacco Leaves and Their Potential Role in the Formation of "Cherry-Red" Tobacco.

Authors:  Yonglei Jiang; Xing Chen; Gaokun Zhao; Jiahong Liu; Yan Xie; Yong Li; Huaguo Gu; Congming Zou
Journal:  Front Microbiol       Date:  2021-07-16       Impact factor: 5.640

Review 4.  Current status on biochemistry and molecular biology of microbial degradation of nicotine.

Authors:  Raman Gurusamy; Sakthivel Natarajan
Journal:  ScientificWorldJournal       Date:  2013-12-29
  4 in total

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