Literature DB >> 5435681

The stereochemistry of hydrogen elimination during 7,8-double bond formation by Tetrahymena pyriformis.

D C Wilton, M Akhtar.   

Abstract

It is shown that formation of the 7,8-double bond in the conversion of cholesterol into cholesta-5,7,22-trien-3beta-ol involves the removal of the 7beta- and 8beta-hydrogen atoms.

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Year:  1970        PMID： 5435681      PMCID： PMC1185370          DOI： 10.1042/bj1160337

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  9 in total

1.  THE STEREOSPECIFIC CONVERSION OF STEARIC ACID TO OLEIC ACID.

Authors:  G J SCHROEPFER; K BLOCH
Journal:  J Biol Chem       Date:  1965-01       Impact factor: 5.157

2.  Conversion of 5-alpha-cholestan-3-beta-ol to delta-7-5-alpha-cholesten-3-beta-ol in cockroaches.

Authors:  R B CLAYTON; A M EDWARDS
Journal:  J Biol Chem       Date:  1963-06       Impact factor: 5.157

3.  The biological conversion of 7-dehydrocholesterol into cholesterol and comments on the reduction of double bonds.

Authors:  D C Wilton; K A Munday; S J Skinner; M Akhtar
Journal:  Biochem J       Date:  1968-02       Impact factor: 3.857

4.  Stereospecificity in the enzymatic conversion of delta-7-cholesten-3-beta-ol to 7-dehydrocholesterol.

Authors:  A M Paliokas; G J Schroepfer
Journal:  J Biol Chem       Date:  1968-02-10       Impact factor: 5.157

5.  The conversion of cholesterol to delta-5,7,22-cholestatrien-3-beta-ol by Tetrahymena pyriformis.

Authors:  R L Conner; F B Mallory; J R Landrey; C W Iyengar
Journal:  J Biol Chem       Date:  1969-05-10       Impact factor: 5.157

6.  The reversibility of the delta8-cholestenol-delta7-cholestenol isomerase reaction in cholesterol biosynthesis.

Authors:  D C Wilton; A D Rahimtula; M Akhtar
Journal:  Biochem J       Date:  1969-08       Impact factor: 3.857

7.  The conversion of cholest-7-en-3beta-ol into cholesterol. General comments on the mechanism of the introduction of double bonds in enzymic reactions.

Authors:  S M Dewhurst; M Akhtar
Journal:  Biochem J       Date:  1967-12       Impact factor: 3.857

8.  The stereochemistry of the hydrogen elimination in the biological conversion of cholest-7-en-3-beta-ol into cholesterol.

Authors:  M Akhtar; S Marsh
Journal:  Biochem J       Date:  1967-02       Impact factor: 3.857

9.  The mechanism of the elaboration of ring B in ergosterol biosynthesis.

Authors:  M Akhtar; M A Parvez
Journal:  Biochem J       Date:  1968-07       Impact factor: 3.857
  9 in total
  4 in total

1.  The steric requirements for sterol inhibition of tetrahymanol biosynthesis.

Authors:  R L Conner; J R Landrey
Journal:  Lipids       Date:  1978-10       Impact factor: 1.880

2.  The role of a 5alpha-hydroxylated intermediate in the formation of the 5, 6-double bond in cholesterol biosynthesis.

Authors:  K Alexander; M Akhtar
Journal:  Biochem J       Date:  1975-02       Impact factor: 3.857

3.  The stereochemistry of hydrogen elimination from C-7 during biosynthesis of ecdysones in insects and plants.

Authors:  I F Cook; J G Lloyd-Jones; H H Rees; T W Goodwin
Journal:  Biochem J       Date:  1973-09       Impact factor: 3.857

4.  Studies on the biosynthesis of tetrahymanol in Tetrahymena pyriformis. The mechanism of inhibition by cholesterol.

Authors:  A S Beedle; K A Munday; D C Wilton
Journal:  Biochem J       Date:  1974-07       Impact factor: 3.857
  4 in total

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