Literature DB >> 5432573

Mercury poisoning: prevention by spironolactone.

H Selye.   

Abstract

The renal tubular necrosis and calcification as well as the mortality induced by mercuric chloride in the rat are readily prevented by prior treatment with well-tolerated amounts of spironolactone.

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Year:  1970        PMID： 5432573     DOI： 10.1126/science.169.3947.775

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  7 in total

1.  Protection by estrogenic hormone against nephrotoxicity induced by organic mercury.

Authors:  K Lehotzky
Journal:  Int Arch Arbeitsmed       Date:  1972

2.  Protection by spironolactone and different antidotes against acute organic mercury poisoning of rats.

Authors:  K Lehotzky
Journal:  Int Arch Arbeitsmed       Date:  1974

Review 3.  Protection by catatoxic steroids against cyclophosphamide-induced organ lesions.

Authors:  H Selye
Journal:  Virchows Arch A Pathol Pathol Anat       Date:  1970

4.  Enhancement of hepatic detoxification enzyme activity by dietary mercuric acetate.

Authors:  D J Wagstaff
Journal:  Bull Environ Contam Toxicol       Date:  1973-01       Impact factor: 2.151

5.  Effect of catatoxic steroids upon established morbid changes.

Authors:  H Selye
Journal:  Experientia       Date:  1971-12-15

6.  The influence of unithiol and spironolactone on the biliary excretion of 203Hg in rat.

Authors:  M Cikrt
Journal:  Arch Toxicol       Date:  1978-01-25       Impact factor: 5.153

7.  Administration of thimerosal to infant rats increases overflow of glutamate and aspartate in the prefrontal cortex: protective role of dehydroepiandrosterone sulfate.

Authors:  Michalina Duszczyk-Budhathoki; Mieszko Olczak; Malgorzata Lehner; Maria Dorota Majewska
Journal:  Neurochem Res       Date:  2011-10-21       Impact factor: 3.996
  7 in total

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