Literature DB >> 541422

Measurement of adriamycin (doxorubicin) and its metabolites in human plasma using reversed-phase high-performance liquid chromatography and fluorescence detection.

R N Pierce, P I Jatlow.   

Abstract

We describe a method for measuring adriamycin and its major metabolite, adriamycinol, in plasma, using reversed-phase high-performance liquid chromatography and fluorescence detection. The lower limit of detection is approximately 1 ng/ml for both compounds; within-day coefficients of variation are 3.6% and 4.4% for adriamycin and adriamycinol, respectively. A slight modification of this procedure also allows measurement of aglycone metabolites.

Entities:  

Mesh：

Substances：

Year:  1979        PMID： 541422     DOI： 10.1016/s0378-4347(00)81549-2

Source DB:  PubMed          Journal:  J Chromatogr


  8 in total

1.  Iron oxide nanoparticle-based magnetic resonance method to monitor release kinetics from polymeric particles with high resolution.

Authors:  Minnie Chan; Eric Schopf; Jagadis Sankaranarayanan; Adah Almutairi
Journal:  Anal Chem       Date:  2012-09-04       Impact factor: 6.986

2.  A simplified method for determination of daunorubicin, adriamycin, and their chief fluorescent metabolites in human plasma by high-pressure liquid chromatography.

Authors:  W Bolanowska; T Gessner; H Preisler
Journal:  Cancer Chemother Pharmacol       Date:  1983       Impact factor: 3.333

3.  Improved high-performance liquid chromatography assay of doxorubicin: detection of circulating aglycones in human plasma and comparison with thin-layer chromatography.

Authors:  D E Brenner; S Galloway; J Cooper; R Noone; K R Hande
Journal:  Cancer Chemother Pharmacol       Date:  1985       Impact factor: 3.333

Review 4.  Anthracycline antitumour agents. A review of physicochemical, analytical and stability properties.

Authors:  J Bouma; J H Beijnen; A Bult; W J Underberg
Journal:  Pharm Weekbl Sci       Date:  1986-04-25

5.  HPLC analysis of doxorubicin, epirubicin and fluorescent metabolites in biological fluids.

Authors:  C M Camaggi; R Comparsi; E Strocchi; F Testoni; F Pannuti
Journal:  Cancer Chemother Pharmacol       Date:  1988       Impact factor: 3.333

6.  Tissue distribution of doxorubicin associated with polyisohexylcyanoacrylate nanoparticles.

Authors:  C Verdun; F Brasseur; H Vranckx; P Couvreur; M Roland
Journal:  Cancer Chemother Pharmacol       Date:  1990       Impact factor: 3.333

Review 7.  Clinical pharmacokinetics of commonly used anticancer drugs.

Authors:  F M Balis; J S Holcenberg; W A Bleyer
Journal:  Clin Pharmacokinet       Date:  1983 May-Jun       Impact factor: 6.447

8.  A rapid chromatographic procedure for the determination of adriamycin, daunomycin and their 13-OH metabolites adriamycinol and daunomycinol.

Authors:  N Erb; R Erttmann; G Landbeck
Journal:  Cancer Chemother Pharmacol       Date:  1986       Impact factor: 3.333
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.