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Literature DB >> 3520474

Anthracycline antitumour agents. A review of physicochemical, analytical and stability properties.

J Bouma, J H Beijnen, A Bult, W J Underberg.

Abstract

A review of physicochemical and analytical properties of anthracycline antitumour agents is presented. The following subjects are discussed: protolytic equilibria, partition and partition coefficients, self-association, adsorptive properties, metal complexation, spectroscopy and chromatography. Furthermore, the stability of anthracyclines in solutions, in pharmaceutical preparations and in biological media is discussed.

Entities: Chemical

Mesh：

Substances：

Year: 1986 PMID： 3520474 DOI： 10.1007/bf02086146

Source DB: PubMed Journal: Pharm Weekbl Sci ISSN： 0167-6555

292 in total

1. Comparison of biochemical and biological methods in the evaluation of new anthracycline drugs.

Authors: A Di Marco; F Zunino; A M Casazza
Journal: Antibiot Chemother (1971) Date: 1978

2. Relationship between effects on nucleic acid synthesis in cell cultures and cytotoxicity of 4-demethoxy derivatives of daunorubicin and adriamycin.

Authors: R Supino; A Necco; T Dasdia; A M Casazza; A Di Marco
Journal: Cancer Res Date: 1977-12 Impact factor: 12.701

3. Photolytic destruction of adriamycin.

Authors: J P Daugherty; S C Hixon
Journal: J Pharm Pharmacol Date: 1981-08 Impact factor: 3.765

4. Effect of route administration and liposome entrapment on the metabolism and disposition of adriamycin in the rat.

Authors: R J Parker; E R Priester; S M Sieber
Journal: Drug Metab Dispos Date: 1982 Sep-Oct Impact factor: 3.922

5. Comparative cytotoxicities of various morpholinyl anthracyclines.

Authors: D G Streeter; D L Taylor; E M Acton; J H Peters
Journal: Cancer Chemother Pharmacol Date: 1985 Impact factor: 3.333

6. Interaction of new anthracycline antibiotics with DNA. Effects on nucleic acid synthesis and binding to DNA.

Authors: T Komiyama; T Oki; T Inui
Journal: Biochim Biophys Acta Date: 1983-05-20

7. Free radical damage to deoxyribose by anthracycline, aureolic acid and aminoquinone antitumour antibiotics. An essential requirement for iron, semiquinones and hydrogen peroxide.

Authors: J M Gutteridge; G J Quinlan
Journal: Biochem Pharmacol Date: 1985-12-01 Impact factor: 5.858

8. Use of anionic liposomes for the reduction of chronic doxorubicin-induced cardiotoxicity.

Authors: E A Forssen; Z A Tökès
Journal: Proc Natl Acad Sci U S A Date: 1981-03 Impact factor: 11.205

9. Tissue distribution and antitumor effect of liposome-entrapped doxorubicin (adriamycin) in Ehrlich solid tumor-bearing mouse.

Authors: S Shinozawa; Y Araki; T Oda
Journal: Acta Med Okayama Date: 1981-12 Impact factor: 0.892

10. Comparison of lipid peroxidation and myocardial damage induced by adriamycin and 4'-epiadriamycin in mice.

Authors: S F Llesuy; J Milei; H Molina; A Boveris; S Milei
Journal: Tumori Date: 1985-06-30

8 in total

1. Nanostructured Surfaces to Target and Kill Circulating Tumor Cells While Repelling Leukocytes.

Authors: Michael J Mitchell; Carlos A Castellanos; Michael R King
Journal: J Nanomater Date: 2012 Impact factor: 2.986

2. E-selectin liposomal and nanotube-targeted delivery of doxorubicin to circulating tumor cells.

Authors: Michael J Mitchell; Christina S Chen; Varun Ponmudi; Andrew D Hughes; Michael R King
Journal: J Control Release Date: 2012-03-01 Impact factor: 9.776

3. Immobilization of a primary amine-containing drug, adriamycin. Coupling to crosslinked polyvinyl alcohol and mechanistic comparison of hydrolytic stability.

Authors: L B Wingard; K Narasimhan
Journal: Appl Biochem Biotechnol Date: 1988-11 Impact factor: 2.926