Literature DB >> 5409709

Countercurrent chromatography: liquid-liquid partition chromatography without solid support.

Y Ito, R L Bowman.   

Abstract

The liquid-liquid partition chromatographic system reported here involves a long helix of narrow-bore tubing. When the coiled tube is filled with one phase of a two-phase system and fed with the other phase, phase-interchange takes place in each turn of the coil, leaving a segment of the former phase as the stationary phase. Consequently, solutes present in either phase are subjected to a multistep partition process. The column efficiency, estimated on a separation of dinitrophenyl amino acids, is comparable to that of gas chromatography.

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Year:  1970        PMID： 5409709     DOI： 10.1126/science.167.3916.281

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  28 in total

Review 1.  Spiral countercurrent chromatography.

Authors:  Yoichiro Ito; Martha Knight; Thomas M Finn
Journal:  J Chromatogr Sci       Date:  2013-08       Impact factor: 1.618

2.  Purification of Proteins From Cell-Culture Medium or Cell-Lysate by High-Speed Counter-Current Chromatography Using Cross-Axis Coil Planet Centrifuge.

Authors:  Yoichi Shibusawa; Yoichiro Ito
Journal:  Open Anal Chem J       Date:  2007

3.  Recent progress on countercurrent chromatography modeling.

Authors:  Fengkang Wang; Yoichiro Ito; Yun Wei
Journal:  J Liq Chromatogr Relat Technol       Date:  2015       Impact factor: 1.312

Review 4.  Countercurrent Separation of Natural Products: An Update.

Authors:  J Brent Friesen; James B McAlpine; Shao-Nong Chen; Guido F Pauli
Journal:  J Nat Prod       Date:  2015-07-15       Impact factor: 4.050

5.  Sweet spot matching: A thin-layer chromatography-based countercurrent solvent system selection strategy.

Authors:  Yang Liu; J Brent Friesen; Edyta M Grzelak; Qingfei Fan; Ting Tang; Kemal Durić; Birgit U Jaki; James B McAlpine; Scott G Franzblau; Shao-Nong Chen; Guido F Pauli
Journal:  J Chromatogr A       Date:  2017-04-27       Impact factor: 4.759

6.  Preparation of two novel monobrominated 2-(2',4'-dihydroxybenzoyl)-3,4,5,6-tetrachlorobenzoic acids and their separation from crude synthetic mixtures using vortex counter-current chromatography.

Authors:  Adrian Weisz; Jacob J Witten; Yun Zeng; Eugene P Mazzola; Yoichiro Ito
Journal:  J Chromatogr A       Date:  2012-03-19       Impact factor: 4.759

7.  Counter-current motion in counter-current chromatography.

Authors:  Yoichiro Ito
Journal:  J Chromatogr A       Date:  2014-09-20       Impact factor: 4.759

8.  Combination of Sonodynamic and Photodynamic Therapy against Cancer Would Be Effective through Using a Regulated Size of Nanoparticles.

Authors:  N Miyoshi; S K Kundu; T Tuziuti; K Yasui; I Shimada; Y Ito
Journal:  Nanosci Nanoeng       Date:  2016-02

9.  Counter-current chromatographic separation of nucleic acid constituents with a hydrophilic solvent system.

Authors:  Yoichi Shibusawa; Atsushi Shoji; Chihiro Suzuka; Akio Yanagida; Yoichiro Ito
Journal:  J Chromatogr A       Date:  2010-03-16       Impact factor: 4.759

10.  Development of a method to extract and purify target compounds from medicinal plants in a single step: online hyphenation of expanded bed adsorption chromatography and countercurrent chromatography.

Authors:  Yang Li; Nan Wang; Min Zhang; Yoichiro Ito; Hongyang Zhang; Yuerong Wang; Xin Guo; Ping Hu
Journal:  Anal Chem       Date:  2014-03-13       Impact factor: 6.986
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