Literature DB >> 540106

A study of the effect of povidone-iodine on polymorphonuclear leucocyte chemotaxis.

J C Connolly, O J Gilmore.   

Abstract

Studies were made of the effect of povidone-iodine on polymorphonuclear leucocyte chemotaxis. Polymorphonuclear leucocytes were incubated with various concentrations of povidone-iodine and allowed to migrate across a membrane towards a chemotactic agent. Chemotactic movement was found to decrease as the concentration of povidone-iodine rose, 75 micrograms/ml completely inhibiting all movement. A concentration of 10 micrograms/ml of povidone-iodine was found actively to repel the white cells. In vivo studies in mice showed a reduction in polymorphonuclear leucocytes at wound surfaces in the presence of povidone-iodine dry powder spray.

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Year:  1979        PMID: 540106      PMCID: PMC2041565     

Source DB:  PubMed          Journal:  Br J Exp Pathol        ISSN: 0007-1021


  12 in total

1.  Effect of aminoglycosides on the chemotactic response of human polymorphonuclear leukocytes.

Authors:  G L Goodhart
Journal:  Antimicrob Agents Chemother       Date:  1977-10       Impact factor: 5.191

2.  Evaluation of tetracycline in the neutrophil chemotactic response.

Authors:  J A Majeski; J W Alexander
Journal:  J Lab Clin Med       Date:  1977-08

3.  Mechanisms of the adjuvant effect of hemoglobin in experimental peritonitis. I. In vivo inhibition of peritoneal leukocytosis.

Authors:  T Hau; R Hoffman; R L Simmons
Journal:  Surgery       Date:  1978-02       Impact factor: 3.982

4.  Aetiology and prevention of wound infection in appendicetomy.

Authors:  O J Gilmore; T D Martin
Journal:  Br J Surg       Date:  1974-04       Impact factor: 6.939

5.  Bacterial factors chemotactic for polymorphonuclear leukocytes.

Authors:  P A Ward; I H Lepow; L J Newman
Journal:  Am J Pathol       Date:  1968-04       Impact factor: 4.307

6.  Effects of tetracycline on leukotaxis.

Authors:  R R Martin; G A Warr; R B Couch; H Yeager; V Knight
Journal:  J Infect Dis       Date:  1974-02       Impact factor: 5.226

7.  Prophylactic interparietal povidone-iodine in abdominal surgery.

Authors:  O J Gilmore; P J Sanderson
Journal:  Br J Surg       Date:  1975-10       Impact factor: 6.939

8.  A study of the effect of povidone-iodine on wound healing.

Authors:  O J Gilmore; C Reid; A Strokon
Journal:  Postgrad Med J       Date:  1977-03       Impact factor: 2.401

9.  Effect of antibiotics of chemotaxis of human leukocytes.

Authors:  A Forsgren; D Schmeling
Journal:  Antimicrob Agents Chemother       Date:  1977-04       Impact factor: 5.191

10.  The chemotactic effect of mixtures of antibody and antigen on polymorphonuclear leucocytes.

Authors:  S BOYDEN
Journal:  J Exp Med       Date:  1962-03-01       Impact factor: 14.307

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  3 in total

Review 1.  Topical Management of Wound: A Narrative Review of Cadexomer Iodine Ointment Versus Povidone Iodine Ointment.

Authors:  Shubham Gupta; Sangita Shinde; Raju K Shinde
Journal:  Cureus       Date:  2022-04-29

2.  Effect of chlorhexidine and acetic acid on phagocytosis by polymorphonuclear leucocytes.

Authors:  J J van Saene; S I Veringa; H K van Saene; J Verhoef; C F Lerk
Journal:  Eur J Clin Microbiol       Date:  1985-10       Impact factor: 3.267

3.  Interaction of povidone-iodine compounds, phagocytic cells, and microorganisms.

Authors:  P J Van den Broek; L F Buys; R Van Furth
Journal:  Antimicrob Agents Chemother       Date:  1982-10       Impact factor: 5.191

  3 in total

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