Literature DB >> 539911

Effect of N,N'-bis(methylisatin-beta-thiosemicarbazone)-2-methylpiperazine on vaccinia virus replication in vitro and in vivo. Brief report.

J Borysiewicz, W Witaliński.   

Abstract

The inhibitory effect of N,N'-bis(methylisatin-beta-thiosemicarbazone)-2-methylpiperazine (compound TSKI-VI) and methisazone (Marboran) on the growth of vaccinia virus (IHD strain) was studied in vitro and in vivo. The therapeutic indices of both compounds determined in vivo were similar, but TSKI-VI was found more efficient in vitro.

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Year:  1979        PMID： 539911     DOI： 10.1007/BF01314907

Source DB:  PubMed          Journal:  Arch Virol        ISSN： 0304-8608            Impact factor:   2.574


  9 in total

1.  Computer evaluation of antiviral activities of some thiosemicarbazones in experiments in vivo.

Authors:  J Borysiewicz; R Tadeusiewicz
Journal:  Acta Virol       Date:  1976-10       Impact factor: 1.162

2.  PROPHYLACTIC TREATMENT OF SMALL POX CONTACTS WITH N-METHYLISATIN BETA-THIOSEMICARBAZONE (COMPOUND 33T57, MARBORAN).

Authors:  D J BAUER; L STVINCENT; C H KEMPE; A W DOWNIE
Journal:  Lancet       Date:  1963-09-07       Impact factor: 79.321

3.  New antiviral chemotherapeutic agent active against smallpox infection.

Authors:  D J BAUER; P W SADLER
Journal:  Lancet       Date:  1960-05-21       Impact factor: 79.321

4.  Experimental chemotherapy of influenza virus with particular reference to thiosemicarbazones and diphenyl compounds.

Authors:  G S LUM; P K SMITH
Journal:  J Pharmacol Exp Ther       Date:  1957-02       Impact factor: 4.030

5.  The antiviral activity of isatin beta-thiosemicarbazone derivatives on vaccinia virus infection in mice.

Authors:  I Zgórniak-Nowosielska; A Gatkiewicz; Z Poteć
Journal:  Arch Immunol Ther Exp (Warsz)       Date:  1976       Impact factor: 4.291

6.  Antiviral agents. 5H-as-Triazino(5,6-b) indoles.

Authors:  J M Gladych; R Hornby; J H Hunt; D Jack; J J Boyle; R J Ferlauto; R F Haff; C G Kormendy; F J Stanfield; R C Stewart
Journal:  J Med Chem       Date:  1972-03       Impact factor: 7.446

7.  Mannich bases, derivatives of isatin and its beta-thiosemicarbazone.

Authors:  B Lucka-Sobstel; A Zejc
Journal:  Acta Microbiol Pol A       Date:  1973

8.  [Kaposi-Juliusberg varioliform pustulosis in an 11-year-old girl. Value of methisazone treatment].

Authors:  J M Estavoyer; C Sainmont; M C Menget; D Caperan; G H Baufle; A Raffi
Journal:  Pediatrie       Date:  1976-04

9.  The effect of certain mannich N-bases, derivatives of isatin beta-thiosemicarbazone, on the replication of vaccinia virus in in vitro studies.

Authors:  J Borysiewicz; B Lucka-Sobstel
Journal:  Acta Microbiol Pol       Date:  1978
  9 in total
  1 in total

1.  Inhibition of Chikungunya Virus Replication by 1-[(2-Methylbenzimidazol-1-yl) Methyl]-2-Oxo-Indolin-3-ylidene] Amino] Thiourea(MBZM-N-IBT).

Authors:  Priyadarsee Mishra; Abhishek Kumar; Prabhudutta Mamidi; Sameer Kumar; Itishree Basantray; Tanuja Saswat; Indrani Das; Tapas Kumar Nayak; Subhasis Chattopadhyay; Bharat Bhusan Subudhi; Soma Chattopadhyay
Journal:  Sci Rep       Date:  2016-02-04       Impact factor: 4.379
  1 in total

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