Immunotherapy of non-clinical vaginal cancer.

In six women who had had a hysterectomy and three or more vaginal smears positive for malignant cells but no symptoms, a course of immunotherapy, based on delayed hypersensitivity reaction to dinitrochlorobenzene, was tried. Repeat smears done every three months have all been normal, and the patients were well when last seen 2-35 months after treatment.