Literature DB >> 535900

Genetic studies of complement C4 in man.

G B Petersen, I J Sørensen, L Buskjaer, L U Lamm.   

Abstract

A C4 variant found in about 5% of the population is described. The fast-moving part of this variant is governed by an allele (Fx) codominant to F. The Fx allele is in very strong linkage disequilibrium with HLA-B17 as the linkage disequilibrium parameter accounted for nearly 100% of the haplotype frequency of B17,Fx. The strong association is also evidenced by the study of 11 families segregating for the Fx allele. There was no instance of recombination between C4 and HLA in 36 informative meioses.

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Year:  1979        PMID： 535900     DOI： 10.1007/BF00289447

Source DB:  PubMed          Journal:  Hum Genet        ISSN： 0340-6717            Impact factor:   4.132


  10 in total

1.  Genetic polymorphism of C4 in man and localisation of a structural C4 locus to the HLA gene complex of chromosome 6.

Authors:  P Teisberg; I Akesson; B Olaisen; T Gedde-Dahl; E Thorsby
Journal:  Nature       Date:  1976-11-18       Impact factor: 49.962

2.  Linkage between the gene (or genes) controlling synthesis of the fourth component of complement and the major histocompatibility complex.

Authors:  H D Ochs; S I Rosenfeld; E D Thomas; E R Giblett; C A Alper; B Dupont; J G Schaller; B C Gilliland; J A Hansen; R J Wedgwood
Journal:  N Engl J Med       Date:  1977-03-03       Impact factor: 91.245

3.  Two HLA-linked loci controlling the fourth component of human complement.

Authors:  G J O'Neill; S Y Yang; B Dupont
Journal:  Proc Natl Acad Sci U S A       Date:  1978-10       Impact factor: 11.205

4.  Electrophoretic polymorphism of the fourth component of human complement (C4) in paired maternal and foetal plasmas.

Authors:  S Bach; S Ruddy; J A MacLaren; K F Austen
Journal:  Immunology       Date:  1971-11       Impact factor: 7.397

5.  Structural polymorphism of the fourth component of human complement.

Authors:  S I Rosenfeld; S Ruddy; K F Austen
Journal:  J Clin Invest       Date:  1969-12       Impact factor: 14.808

6.  Genetic polymorphism of the fourth component of human complement.

Authors:  G Mauff; K Bender; B Fischer
Journal:  Vox Sang       Date:  1978       Impact factor: 2.144

7.  Chido and Rodgers blood groups are distinct antigenic components of human complement C4.

Authors:  G J O'Neill; S Y Yang; J Tegoli; R Berger; B Dupont
Journal:  Nature       Date:  1978-06-22       Impact factor: 49.962

8.  On the mapping of PGM3, GLO and HLA.

Authors:  L U Lamm; L R Weitkamp; O Jensson; G B Pedersen; F Kissmeyer-Nielsen
Journal:  Tissue Antigens       Date:  1978-02

9.  The genetic polymorphism of the fourth component of human complement: methodological aspects and a presentation of linkage and association data relevant to its localization in the HLA region.

Authors:  P Teisberg; B Olaisen; R Jonassen; T Gedde-Dahl; E Thorsby
Journal:  J Exp Med       Date:  1977-11-01       Impact factor: 14.307

10.  Genetic polymorphism in human glycine-rich beta-glycoprotein.

Authors:  C A Alper; T Boenisch; L Watson
Journal:  J Exp Med       Date:  1972-01       Impact factor: 14.307
  10 in total
  3 in total

1.  Analysis of active and inactive complement C4 complotypes associated with subtypes of HLA-B17 in different racial groups.

Authors:  G J O'Neill; C Nerl; M S Pollack
Journal:  Am J Hum Genet       Date:  1983-03       Impact factor: 11.025

2.  Family studies of complement C4 and HLA in man.

Authors:  G Bruun-Petersen; L U Lamm; I J Sørensen; L Buskjaer; J P Mortensen
Journal:  Hum Genet       Date:  1981       Impact factor: 4.132

3.  Human C4 polymorphism: pedigree analysis of qualitative, quantitative, and functional parameters as a basis for phenotype interpretations.

Authors:  G Mauff; K Bender; C M Giles; S Goldmann; W Opferkuch; B Wachauf
Journal:  Hum Genet       Date:  1984       Impact factor: 4.132
  3 in total

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