Literature DB >> 534506

Decarboxylation of porphyrinogens by rat liver uroporphyrinogen decarboxylase.

A G Smith, J E Francis.   

Abstract

The decarboxylations of uroporphyrinogens I and III and of heptacarboxylic, hexacarboxylic and pentacarboxylic porphyrinogens III by rat liver uroporphyrinogen decarboxylase were compared, and the results suggest that the removal of the first carboxy group from uroporphyrinogen III is a more rapid step than that from isomer I or the other substrates investigated.

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Year:  1979        PMID： 534506      PMCID： PMC1161576          DOI： 10.1042/bj1830455

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  13 in total

1.  Decarboxylation of uroporphyrin by heating at atmospheric pressure.

Authors:  T K With
Journal:  Biochem J       Date:  1975-05       Impact factor: 3.857

2.  A qualitative and quantitative study of the separation of uroporphyrin octamethyl esters I and III by dioxan chromatography.

Authors:  P A CORNFORD; A BENSON
Journal:  J Chromatogr       Date:  1963-02

3.  Porphyrin biosynthesis in erythrocytes. III. Uroporphyrinogen and its decarboxylase.

Authors:  D MAUZERALL; S GRANICK
Journal:  J Biol Chem       Date:  1958-06       Impact factor: 5.157

4.  Protein measurement with the Folin phenol reagent.

Authors:  O H LOWRY; N J ROSEBROUGH; A L FARR; R J RANDALL
Journal:  J Biol Chem       Date:  1951-11       Impact factor: 5.157

5.  Macrocyclic intermediates in the biosynthesis of porphyrins.

Authors:  A H Jackson; H A Sancovich; A M Ferramola; N Evans; D E Games; S A Matlin; G H Elder; S G Smith
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  1976-02-05       Impact factor: 6.237

6.  The pattern of porphyrin isomer accumulation and excretion in symptomatic porphyria.

Authors:  E Dowdle; P Goldswain; N Spong; L Eales
Journal:  Clin Sci       Date:  1970-08       Impact factor: 6.124

7.  Transformation of porphobilinogen into porphyrins by preparations from human erythrocytes.

Authors:  P Cornford
Journal:  Biochem J       Date:  1964-04       Impact factor: 3.857

8.  Uroporphyrinogen decarboxylase from mouse spleen.

Authors:  G Romeo; E Y Levin
Journal:  Biochim Biophys Acta       Date:  1971-02-23

9.  The enzymatic decarboxylation of the naturally occurring isomers of uroporphyrinogen by human erythrocytes.

Authors:  G L Rasmussen; J P Kushner
Journal:  J Lab Clin Med       Date:  1979-01

10.  The substrate specificity and stereochemistry, reversibility and inhibition of the 3-oxo steroid delta 4-delta 5-isomerase component of cholesterol oxidase.

Authors:  A G Smith; C J Brooks
Journal:  Biochem J       Date:  1977-10-01       Impact factor: 3.857
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  16 in total

Review 1.  Structure and function of enzymes in heme biosynthesis.

Authors:  Gunhild Layer; Joachim Reichelt; Dieter Jahn; Dirk W Heinz
Journal:  Protein Sci       Date:  2010-06       Impact factor: 6.725

2.  The effects in vivo of mutationally modified uroporphyrinogen decarboxylase in different hem12 mutants of baker's yeast (Saccharomyces cerevisiae).

Authors:  A Kurlandzka; T Zoladek; J Rytka; R Labbe-Bois; D Urban-Grimal
Journal:  Biochem J       Date:  1988-07-01       Impact factor: 3.857

3.  Inhibition of uroporphyrinogen decarboxylase activity. The role of cytochrome P-450-mediated uroporphyrinogen oxidation.

Authors:  R W Lambrecht; J M Jacobs; P R Sinclair; J F Sinclair
Journal:  Biochem J       Date:  1990-07-15       Impact factor: 3.857

4.  Purification and properties of the uroporphyrinogen decarboxylase from Rhodobacter sphaeroides.

Authors:  R M Jones; P M Jordan
Journal:  Biochem J       Date:  1993-08-01       Impact factor: 3.857

5.  Quantitative analysis of flux along the gluconeogenic, glycolytic and pentose phosphate pathways under reducing conditions in hepatocytes isolated from fed rats.

Authors:  J M Crawford; J J Blum
Journal:  Biochem J       Date:  1983-06-15       Impact factor: 3.857

6.  Formation of N-methyl protoporphyrin in chemically-induced protoporphyria. Studies with a novel porphyrogenic agent.

Authors:  Y Frater; A Brady; E A Lock; F De Matteis
Journal:  Arch Toxicol       Date:  1993       Impact factor: 5.153

7.  Modified uroporphyrinogen decarboxylase activity in a yeast mutant which mimics porphyria cutanea tarda.

Authors:  J Rytka; T Bilinski; R Labbe-Bois
Journal:  Biochem J       Date:  1984-03-01       Impact factor: 3.857

8.  N-alkylation of the haem moiety of cytochrome P-450 caused by substituted dihydropyridines. Preferential attack of different pyrrole nitrogen atoms after induction of various cytochrome P-450 isoenzymes.

Authors:  F De Matteis; A H Gibbs; C Hollands
Journal:  Biochem J       Date:  1983-05-01       Impact factor: 3.857

9.  Uroporphyria produced in mice by 20-methylcholanthrene and 5-aminolaevulinic acid.

Authors:  A J Urquhart; G H Elder; A G Roberts; R W Lambrecht; P R Sinclair; W J Bement; N Gorman; J A Sinclair
Journal:  Biochem J       Date:  1988-07-15       Impact factor: 3.857

10.  Formation of N-alkylated protoporphyrin IX in the livers of mice after diethylnitrosamine treatment.

Authors:  I N White; A G Smith; P B Farmer
Journal:  Biochem J       Date:  1983-06-15       Impact factor: 3.857
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