Literature DB >> 53257

Induction of antiphosphorylcholine antibody formation by anti-idiotypic antibodies.

E Trenkner, R Riblet.   

Abstract

Anti-idiotypic antibodies have been used to mimic antigen in the mouse antiphosphorylcholine response in order to investigate the induction of precursors of antibody-forming cells. We have shown that interaction of anti-idiotype antibody with receptor antibody molecules induces the formation of antibodies that are specific for phosphorylcholine and carry the idiotypic determinants. This induction is dependent on the recognition of carrier determinants on the anti-idiotype antibody by helper T cells. We conclude that receptor antibody molecules on the surface of the precursors of antibody-forming cells deliver the antigenic signal for the induction of these cells.

Entities:  

Mesh：

Substances：

Year:  1975        PMID： 53257      PMCID： PMC2189971          DOI： 10.1084/jem.142.5.1121

Source DB:  PubMed          Journal:  J Exp Med        ISSN： 0022-1007            Impact factor:   14.307


  21 in total

Review 1.  Membrane immunoglobulins and antigen receptors on B and T lymphocytes.

Authors:  N L Warner
Journal:  Adv Immunol       Date:  1974       Impact factor: 3.543

Review 2.  The control of humoral and associative antibody synthesis.

Authors:  P Bretscher
Journal:  Transplant Rev       Date:  1972

3.  Inheritance of an idiotype associated with the immune response of inbred mice to phosphorylcholine.

Authors:  A Sher; M Cohn
Journal:  Eur J Immunol       Date:  1972-08       Impact factor: 5.532

4.  Towards a network theory of the immune system.

Authors:  N K Jerne
Journal:  Ann Immunol (Paris)       Date:  1974-01

5.  Genetics of the antibody response to dextran in mice.

Authors:  B Blomberg; W R Geckeler; M Weigert
Journal:  Science       Date:  1972-07-14       Impact factor: 47.728

6.  Immunoglobulin structure: amino terminal sequences of mouse myeloma proteins that bind phosphorylcholine.

Authors:  P Barstad; S Rudikoff; M Potter; M Cohn; W Konigsberg; L Hood
Journal:  Science       Date:  1974-03-08       Impact factor: 47.728

7.  Genetics of a new IgVH (T15 idiotype) marker in the mouse regulating natural antibody to phosphorylcholine.

Authors:  R Lieberman; M Potter; E B Mushinski; W Humphrey; S Rudikoff
Journal:  J Exp Med       Date:  1974-04-01       Impact factor: 14.307

8.  Common individual antigenic determinants in five of eight BALB-c IgA myeloma proteins that bind phosphoryl choline.

Authors:  M Potter; R Lieberman
Journal:  J Exp Med       Date:  1970-10-01       Impact factor: 14.307

9.  Clonal nature of the immune response to phosphorylcholine. I. Specificity, class, and idiotype of phosphorylcholine-binding receptors on lymphoid cells.

Authors:  J L Claflin; R Lieberman; J M Davie
Journal:  J Exp Med       Date:  1974-01-01       Impact factor: 14.307

10.  Isolation of antigen-binding cells from unprimed mice: demonstration of antibody-forming cell precursor activity and correlation between precursor and secreted antibody avidities.

Authors:  M H Julius; L A Herzenberg
Journal:  J Exp Med       Date:  1974-10-01       Impact factor: 14.307
View more
  24 in total

1.  Unreasonable implications of reasonable idiotypic network assumptions.

Authors:  R J De Boer; P Hogeweg
Journal:  Bull Math Biol       Date:  1989       Impact factor: 1.758

Review 2.  Autoregulation of immune responses via idiotype network interactions.

Authors:  L S Rodkey
Journal:  Microbiol Rev       Date:  1980-12

Review 3.  Induction of immune responses with anti-idiotypic antibodies: implications for the induction of protective immunity.

Authors:  D L Sacks; G H Kelsoe; D H Sachs
Journal:  Springer Semin Immunopathol       Date:  1983

4.  The assessment of anti-idiopathic antibodies as effective immunoregulatory probes in vivo.

Authors:  J C Olson; C R Wagner; G A Leslie
Journal:  Clin Exp Immunol       Date:  1982-05       Impact factor: 4.330

5.  Studies on chemically induced tumors in rats: I. Heterogeneity of tumor cells and establishment of syngeneic, tumor-specific cytotoxic T cell clones.

Authors:  H Binz; M Fenner; H Wigzell
Journal:  Experientia       Date:  1983-01-15

6.  Induction of immunity to a human tumor marker by in vivo administration of anti-idiotypic antibodies in mice.

Authors:  G T Nepom; K A Nelson; S L Holbeck; I Hellström; K E Hellström
Journal:  Proc Natl Acad Sci U S A       Date:  1984-05       Impact factor: 11.205

7.  Suppression of in vitro monoclonal human rheumatoid factor synthesis by antiidiotypic antibody. Target cells and molecular requirements.

Authors:  W J Koopman; R E Schrohenloher; J C Barton; E C Greenleaf
Journal:  J Clin Invest       Date:  1983-10       Impact factor: 14.808

8.  Suppression of tumor rejection by autologous anti-idiotypic immunity.

Authors:  P M Flood; M L Kripke; D A Rowley; H Schreiber
Journal:  Proc Natl Acad Sci U S A       Date:  1980-04       Impact factor: 11.205

9.  The application of hybridoma technology to the study of bovine immunoglobulins.

Authors:  R A Goldsby; S Srikumaran; A Arulanandam; B Hague; F A Ponce de Leon; M Sevoian; A J Guidry
Journal:  Vet Immunol Immunopathol       Date:  1987-12       Impact factor: 2.046

10.  Antiidiotype modulation of herpes simplex virus infection leading to increased pathogenicity.

Authors:  R C Kennedy; K Adler-Storthz; J W Burns; R D Henkel; G R Dreesman
Journal:  J Virol       Date:  1984-06       Impact factor: 5.103
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.