Literature DB >> 5312959

Factor 8 detection by hemagglutination inhibition: hemophilia A and von Willebrand's disease.

D P Stites, E J Hershgold, J D Perlman, H H Fudenberg.   

Abstract

Factor VIII activity was detected immunologically in both the serums and plasmas of 14 normal individuals and 14 patients with hemophilia A. A hemagglutination-inhibition test with rabbit antibody to highly purified (10,000-fold) factor VIII from humans was used. Serums and plasmas from eight patients with von Willebrand's disease showed little or no factor VIII activity in this test, an indication that the test may serve as a specific assay for differentiation between von Willebrand's disease and hemophilia A.

Entities:  

Mesh：

Substances：

Year:  1971        PMID： 5312959     DOI： 10.1126/science.171.3967.196

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  21 in total

1.  Problems in the detection of carriers of haemophilia A.

Authors:  D Meyer; A Plas; J P Allain; G M Sitar; M J Larrieu
Journal:  J Clin Pathol       Date:  1975-09       Impact factor: 3.411

Review 2.  Treatment of immune deficiency.

Authors:  H H Fudenberg; L E Spitler; A S Levin
Journal:  Am J Pathol       Date:  1972-12       Impact factor: 4.307

3.  Factor VIII-related antigen in tissues detected by the indirect immunofluorescence technique.

Authors:  R Gruson; C R Rizza
Journal:  Blut       Date:  1974-10

4.  [Increase of factor VIII-(antihemophilic globulin)-activity in plasma of hemophiliacs following addition of synthetic fibrinolytic compounds].

Authors:  E von Kaulla; K N von Kaulla
Journal:  Klin Wochenschr       Date:  1973-07-15

5.  Variations in levels of blood clotting factors IX and X in a population of normal men: possible genetic polymorphisms.

Authors:  R H Lester; R C Elston; J B Graham
Journal:  Am J Hum Genet       Date:  1972-03       Impact factor: 11.025

6.  Inversions in the factor VIII gene: improvement of carrier detection and prenatal diagnosis in Dutch haemophilia A families.

Authors:  P P Deutz-Terlouw; M Losekoot; R Olmer; W C Pieneman; S de Vries-v d Weerd; E Briët; E Bakker
Journal:  J Med Genet       Date:  1995-04       Impact factor: 6.318

7.  Studies on the nature of antihemophilic factor (factor VIII). Further evidence relating the AHF-like antigens in normal and hemophilic plasmas.

Authors:  B Bennett; W B Forman; O D Ratnoff
Journal:  J Clin Invest       Date:  1973-09       Impact factor: 14.808

8.  The subunit structure of normal and hemophilic factor VIII.

Authors:  G A Shapiro; J C Andersen; S V Pizzo; P A McKee
Journal:  J Clin Invest       Date:  1973-09       Impact factor: 14.808

9.  Synthesis of antihemophilic factor antigen by cultured human endothelial cells.

Authors:  E A Jaffe; L W Hoyer; R L Nachman
Journal:  J Clin Invest       Date:  1973-11       Impact factor: 14.808

10.  Genetic variants of von Willebrand's disease.

Authors:  L Holmberg; I M Nilsson
Journal:  Br Med J       Date:  1972-08-05
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.