Literature DB >> 5289366

Insulin-sepharose and the dynamics of insulin action.

T Oka, Y J Topper.   

Abstract

In terms of the rate of accumulation of alpha-aminoisobutyric acid, mammary epithelial cells from mature virgin mice respond rapidly to insulin covalently bound to sepharose particles, but do not respond initially to soluble insulin in vitro. The response to insulin-sepharose is prevented if the cells are first exposed to insulin. These observations may provide new insight into the dynamics of insulin action.

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Year:  1971        PMID： 5289366      PMCID： PMC389352          DOI： 10.1073/pnas.68.9.2066

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  6 in total

1.  The glucagon-sensitive adenyl cyclase system in plasma membranes of rat liver. V. An obligatory role of guanylnucleotides in glucagon action.

Authors:  M Rodbell; L Birnbaumer; S L Pohl; H M Krans
Journal:  J Biol Chem       Date:  1971-03-25       Impact factor: 5.157

2.  A novel action of insulin on phosphoprotein formation by mammary gland explants.

Authors:  A E Voytovich; I S Owens; Y J Topper
Journal:  Proc Natl Acad Sci U S A       Date:  1969-05       Impact factor: 11.205

3.  Multiple hormone interactions related to the growth and differentiation of mammary gland in vitro.

Authors:  Y J Topper
Journal:  Trans N Y Acad Sci       Date:  1968-04

4.  Chemical coupling of proteins to agarose.

Authors:  J Porath; R Axen; S Ernback
Journal:  Nature       Date:  1967-09-30       Impact factor: 49.962

5.  Development of insulin-sensitivity by mouse mammary gland in vitro.

Authors:  S H Friedberg; T Oka; Y J Topper
Journal:  Proc Natl Acad Sci U S A       Date:  1970-11       Impact factor: 11.205

6.  Interaction of insulin with the cell membrane: the primary action of insulin.

Authors:  P Cuatrecasas
Journal:  Proc Natl Acad Sci U S A       Date:  1969-06       Impact factor: 11.205
  6 in total
  10 in total

1.  Affinity chromatography and purification of the insulin receptor of liver cell membranes.

Authors:  P Cuatrecasas
Journal:  Proc Natl Acad Sci U S A       Date:  1972-05       Impact factor: 11.205

2.  Is prolactin mitogenic for mammary epithelium?

Authors:  T Oka; Y J Topper
Journal:  Proc Natl Acad Sci U S A       Date:  1972-07       Impact factor: 11.205

3.  Isolation of the insulin receptor of liver and fat-cell membranes (detergent-solubilized-( 125 I)insulin-polyethylene glycol precipitation-sephadex).

Authors:  P Cuatrecasas
Journal:  Proc Natl Acad Sci U S A       Date:  1972-02       Impact factor: 11.205

4.  Insulin-like activity of concanavalin A and wheat germ agglutinin--direct interactions with insulin receptors.

Authors:  P Cuatrecasas; G P Tell
Journal:  Proc Natl Acad Sci U S A       Date:  1973-02       Impact factor: 11.205

5.  Separation of acinar cells from lactating mammary gland using velocity sedimentation in an isokinetic gradient of Ficoll in tissue culture medium.

Authors:  T G Pretlow; S R Dow; T M Murad; J Jones
Journal:  Am J Pathol       Date:  1974-07       Impact factor: 4.307

6.  Some aspects of mouse mammary gland development from maturity to early pregnancy.

Authors:  Y J Topper; T Oka; I S Owens; B K Vonderhaar
Journal:  In Vitro       Date:  1972 Nov-Dec

7.  A soluble super-active form of insulin.

Authors:  T Oka; Y J Topper
Journal:  Proc Natl Acad Sci U S A       Date:  1974-05       Impact factor: 11.205

8.  Affinity binding of intact fat cells and their ghosts to immobilized insulin.

Authors:  D D Soderman; J Germershauden; H M Katzen
Journal:  Proc Natl Acad Sci U S A       Date:  1973-03       Impact factor: 11.205

9.  Biologically active catecholamines covalentyly bound to glass beads.

Authors:  J C Venter; J E Dixon; P R Maroko; N O Kaplan
Journal:  Proc Natl Acad Sci U S A       Date:  1972-05       Impact factor: 11.205

10.  Glucose-6-phosphate dehydrogenase isoenzymes in acinar epithelial cells separated from the mammary gland of the rat at intervals during the course of lactation.

Authors:  M M Scalise; R B Thorp; T G Pretlow; T M Murad
Journal:  Am J Pathol       Date:  1977-01       Impact factor: 4.307
  10 in total

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