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Literature DB >> 527945

[Increased urinary excretion of neopterin in patients with malignant tumors and with virus diseases (author's transl)].

Abstract

Heightened urinary concentrations of neopterin were detected in patients with malignant tumors. The levels of neopterin were quantified by high performance liquid chromatography. The normal range for male individuals was 280 +/- 1,7 ng neopterin/mg creatinin, for women 340 +/- 116 ng neopterin/mg creatinin. The values found in patients with malignant tumors were 1370 +/- 495 ng neopterin/mg creatinin and in patients with virus diseases 1637 +/- 696 ng neopterin/mg creatinin.

Entities: Chemical Disease Species

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Year: 1979 PMID： 527945

Source DB: PubMed Journal: Hoppe Seylers Z Physiol Chem ISSN： 0018-4888

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Cited

29 in total

1. Unconjugated pteridines and the activation of macrophages by interferon gamma.

Authors: G Reibnegger; D Fuchs; A Hausen; E R Werner; G Werner-Felmayer; H Wachter
Journal: Cancer Chemother Pharmacol Date: 1990 Impact factor: 3.333

2. Elevated serum neopterin levels in sarcoidosis.

Authors: A Eklund; E Blaschke
Journal: Lung Date: 1986 Impact factor: 2.584

3. Value of urinary neopterin in the differential diagnosis of bacterial and viral infections.

Authors: H Denz; D Fuchs; A Hausen; H Huber; D Nachbaur; G Reibnegger; J Thaler; E R Werner; H Wachter
Journal: Klin Wochenschr Date: 1990-02-15

4. Parallel induction of tetrahydrobiopterin biosynthesis and indoleamine 2,3-dioxygenase activity in human cells and cell lines by interferon-gamma.

Authors: E R Werner; G Werner-Felmayer; D Fuchs; A Hausen; G Reibnegger; H Wachter
Journal: Biochem J Date: 1989-09-15 Impact factor: 3.857

9. A survey of the location, isolation and identification of indoles, pteridines and some unknown active substances in sheep pineals. The possible significance of pteridines for the neuroendocrine control of neoplastic growth.

Authors: I Ebels
Journal: J Neural Transm Date: 1980 Impact factor: 3.575

10. [Neopterin in the serum and urine in the differential diagnosis of disorders of kidney function following kidney transplantation].

Authors: J Wolf; E Musch; H Neuss; U Klehr
Journal: Klin Wochenschr Date: 1987-03-02

[Increased urinary excretion of neopterin in patients with malignant tumors and with virus diseases (author's transl)].

1. Unconjugated pteridines and the activation of macrophages by interferon gamma.

2. Elevated serum neopterin levels in sarcoidosis.

3. Value of urinary neopterin in the differential diagnosis of bacterial and viral infections.

4. Parallel induction of tetrahydrobiopterin biosynthesis and indoleamine 2,3-dioxygenase activity in human cells and cell lines by interferon-gamma.

Review 5. Neopterin as a biomarker of immune response in cancer patients.

Review 6. Realising the Potential of Urine and Saliva as Diagnostic Tools in Sport and Exercise Medicine.

7. Intrathecal production of neopterin in aseptic meningo-encephalitis and multiple sclerosis.

8. The clinical significance of serum and urinary neopterin levels in several renal diseases.

9. A survey of the location, isolation and identification of indoles, pteridines and some unknown active substances in sheep pineals. The possible significance of pteridines for the neuroendocrine control of neoplastic growth.

10. [Neopterin in the serum and urine in the differential diagnosis of disorders of kidney function following kidney transplantation].