Literature DB >> 5276306

Model for constraint and control in biochemical networks.

S A Newman, S A Rice.   

Abstract

A model is proposed for biochemical networks which takes into account substrate and modifier effects on enzyme activity and the different time scales on which the relevant processes occur. Sources of global constraint that can be utilized in metabolic regulation are indicated, and the relation of the model to the experiments of Kauffman on switching networks is analyzed. The biological significance of the model and possible systems in which it might be tested are discussed.

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Year:  1971        PMID： 5276306      PMCID： PMC391169          DOI： 10.1073/pnas.68.1.92

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  7 in total

1.  ON THE NATURE OF ALLOSTERIC TRANSITIONS: A PLAUSIBLE MODEL.

Authors:  J MONOD; J WYMAN; J P CHANGEUX
Journal:  J Mol Biol       Date:  1965-05       Impact factor: 5.469

2.  An analog of the Boltzmann H-theorem (a Liapunov function) for systems of coupled chemical reactions.

Authors:  D Shear
Journal:  J Theor Biol       Date:  1967-08       Impact factor: 2.691

3.  Note on complex systems.

Authors:  S A Newman
Journal:  J Theor Biol       Date:  1970-09       Impact factor: 2.691

4.  Metabolic stability and epigenesis in randomly constructed genetic nets.

Authors:  S A Kauffman
Journal:  J Theor Biol       Date:  1969-03       Impact factor: 2.691

5.  On temporal characteristics of behavior in certain complex systems.

Authors:  C C Walker; W R Ashby
Journal:  Kybernetik       Date:  1966-05

6.  Synopsis of organismic theory.

Authors:  W M Elsasser
Journal:  J Theor Biol       Date:  1964-07       Impact factor: 2.691

7.  Differentiation in vitro: effects of Sephadex fractions of chick embryo extract.

Authors:  H G Coon; R D Cahn
Journal:  Science       Date:  1966-09-02       Impact factor: 47.728
  7 in total
  2 in total

1.  The derivation of ecological relationships from physical and chemical principles.

Authors:  H J Morowitz
Journal:  Proc Natl Acad Sci U S A       Date:  1974-06       Impact factor: 11.205

Review 2.  The developmental-genetics of canalization.

Authors:  Benedikt Hallgrimsson; Rebecca M Green; David C Katz; Jennifer L Fish; Francois P Bernier; Charles C Roseman; Nathan M Young; James M Cheverud; Ralph S Marcucio
Journal:  Semin Cell Dev Biol       Date:  2018-05-24       Impact factor: 7.727
  2 in total

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